Drug utilization study of antipsychotics among schizophrenia patients in a tertiary care teaching hospital: a retrospective observational study

Mogali, Sahana M.; Kotinatot, Basavaraj C.

doi:10.18203/2319-2003.ijbcp20202185

Cited by 2 publications

(2 citation statements)

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“…As similar to the trend seen in other studies, olanzapine (n=26) followed by haloperidol (n=15) and risperidone (n=15) were the most commonly prescribed antipsychotics among the study populations. 10,13,25,26 In the present study, only one prescription of clozapine (n=1) has reported which was similar to the previous studies that reported a lower rate of prescription of clozapine. 13,15,27 Majority of the patients with bipolar disorder were prescribed with mood stabilizers and sodium valproate (n=21) is the most commonly prescribed anti-mania medication as compared to lithium (n=4) in the present study.…”

Section: Discussionsupporting

confidence: 90%

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Trends and practices in prescribing anti-psychotropic medications in hospitalized patients with psychiatric disorders in a secondary care hospital in Ras al Khaimah

Shareef

Rao

Ayman

2020

Int J Basic Clin Pharmacol

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Background: Advances in the psycho-pharmacotherapy enhance the development of newer and better drugs in the management of psychiatric disorders. However, their proper utilization, safety and efficacy and adverse effects in the clinical practice needs continuous study. The study aimed to assess the trends and practice of prescribing psychotropic medications in hospitalized patients in a secondary care hospital in Ras Al Khaimah.Methods: A prospective observational study was carried out for a period of six months in a psychiatry department. All the patient details including the demographic data and prescribing pattern of antipsychotic medication were collected from the patient case records and were later analysed by using descriptive statistics.Results: A total of 50 patient’s prescription were analysed during the study period. Male (54%) predominance was noted over females (46%) with majority (64%) of patients were in the age group of 21-40 years. Schizophrenia (35.8%) was the most common psychiatric disorders followed by affective disorders (30.86%). The average number of psychiatric drugs per prescription was found to be 3.38±1.23. Antipsychotics (43.36%) were the commonly prescribed class of medications followed by mood stabilizers (12.38%) and anxiolytics (11.06%) with olanzapine (n=26), sodium valproate (n=21) and clonazepam (n=9) being frequently prescribed medications. Escitalopram (n=9) was the most commonly used anti-depressants. Combination therapy (86%) is preferred over monotherapy (14%).Conclusions: This study helps to assist in ensuring rational drug therapy and reducing the incidence of drug related problems and medication errors and thereby enhancing the quality of care in patients with psychiatric disorders.

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Section: Discussionsupporting

confidence: 90%

“…This finding is higher than that found in similar studies where it ranged from 0.03-6.2% . 11,13,17,25 Haloperidol (40.74%) is the most commonly used parenteral depot preparations in our study. Our findings are in line with the studies examining the use of psychotropic medications in schizophrenia patients in other countries.…”

Section: Discussionmentioning

confidence: 84%