Drug utilization study in post-operative patients in obstetrics and gynecology ward of a tertiary care teaching hospital

Agrawal, Jitendra M.; Patel, Nirav M.; Vaniya, Hardik V.; Trivedi, Hiren R.; Balat, Jayesh D.

doi:10.5455/jcer.201421

Cited by 5 publications

(10 citation statements)

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“…Also the most common antimicrobial used preoperatively in our study was metronidazole followed by ceftriaxone with and amoxicillinclavulanic acid. Similarly in Agrawal et al study, metronidazole topped the list 26 . Metronidazole is used predominantly to cover up for all the anaerobic infections 25 .…”

Section: Discussionmentioning

confidence: 73%

A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

Parulekar¹

2020

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Introduction: Surgical site infection (SSI) is the most common post-operative complication and represents a significant burden in terms of patient morbidity and mortality, and cost to health services around the world. Appropriate antibiotic prophylaxis has been shown to be effective in reducing the incidence of surgical site infections as studies suggest that 40-60% of these infections are preventable. Aims: To evaluate and compare the utilization pattern of antimicrobial agents (AMA) in surgical prophylaxis use in preoperative, intraoperative and post-operative wards of different specialities. Settings and Design: It is a cross-sectional observational study conducted patients admitted to surgery, orthopaedics, ENT and gynaecology wards in tertiary teaching care hospital. Methods and Material: The study duration was from November 2016-November 2018 (2 years).The data was collected time to time from all the medical records of the patient. The study protocol was approved by the Institutional Ethics Committee. Statistical Analysis Used: Data was collected and compiled using Microsoft Excel 2010 and then analysed by calculating simple proportions, frequency and percentage of various parameters. Results: Out of 386 patients, it was observed that female patients (55.69%) were more than male (44.60%) patients. The majority of surgical wounds were clean (39.11%) and most common antimicrobial used pre-operatively was metronidazole (29.24%) and in the intraoperative and postoperative period was gentamicin (54.28%). Number of DDD for inj.amoxicillin-clavulanic acid 1.2g was 274.4. Conclusions: After observing the trend of use of antibiotics, there is a clear need for the development of prescribing guidelines and educational initiatives to encourage the appropriate use of antimicrobials in surgical period. Also, there is scope for improving prescribing habits among the fraternity and minimizing incidence of resistance to antimicrobials.

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Section: Discussionmentioning

confidence: 73%

A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

Parulekar¹

2020

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“…This finding is consistent with Bhataia et al [8] where 5627 total medicine formulations were studied and 98.51% (5534) were found out to be prescribed by official/generic names. Similarly, in Agrawal et al [14] study, 77.77% drugs were prescribed by generic name. Contrary to our study, 48.57% drugs were prescribed by generic name in the Bhansali et al study [4].…”

Section: Discussionmentioning

confidence: 83%

Observing Drug Utilization Trends of Analgesics in Indoor Surgical Patients in Tertiary Care Teaching Hospital

Parulekar

Badar

2020

Asian J Pharm Clin Res

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Objectives: The objectives of the study were to evaluate and compare the utilization pattern of analgesic use in pre-operative, intraoperative, and post-operative wards of different surgical specialties. Methods: It was a prospective, cross-sectional, and observational study done for a period of 1 year and the data were obtained from case sheets of 386 patients admitted in surgical wards of the. Data were analyzed according to demography, type of surgery, and the WHO prescribing indicators. The percentage of analgesic prescribed from an essential medicine list or National list of essential medicine (NLEM), common analgesics, and fixed dose combinations (FDC) used in surgery, gynecology, ENT, and orthopedic wards in preoperatively, intraoperatively, and postoperatively, was assessed and the amounts of drugs consumed were converted into the number of daily defined dose (DDD) as per the 2010 version of ATC/DDD index. Results and Discussion: The female to male ratio of 1.21 and most of patients were in the category of middle-aged adults (49%). On the evaluation of WHO prescribing parameters, it was seen the average number of analgesics prescribed per prescription was 1.26, percentage of injectable analgesics and analgesics prescribed from NLEM were 81.09% and 90.64%, respectively. Perioperatively, injection diclofenac sodium was the most commonly used analgesic and its DDD was 460. The most common FDC used perioperatively was aceclofenac 325mg+serratiopeptidase 15 mg (5.04%) and Drug Controller General of India and the WHO approved FDCs were 80.28% and 75.53%, respectively. Conclusion: It is necessary to determine the prevalence and severity of post-surgical pain and implementation of standardized pain evaluation and treatment protocols which improve the post-operative patient care in the hospital setting.

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“…29 The ideal percentage of injections prescribed according to WHO must be between 13.4% -24.1%, but in our study it was found to be more higher since post-operative gynaecology patients were kept in intravenous line till they were recovered and discharged. Use of more number of injectable drugs was observed by Patel et al while in some studies done by Rehan et al reported use of less number of injectable drugs in north India.…”

Section: -11mentioning

confidence: 76%

“…In our study, (82.16%) were prescribed from the Essential Medicines WHO Model List which was similar to other studies like Agarwal et al (85.1%) and Falguni et al (92.8%). 29,32 Prescribing according to the national essential list of medicines was high, which indicates rational prescription.…”

Section: -11mentioning

confidence: 99%

Prescribing pattern and WHO core prescribing indicators in post-operative patients of Gynaecology department of a Tertiary Care Teaching Hospital

Kolasani

Sasidharan

Divyashanthi

et al. 2017

Int J Basic Clin Pharmacol

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Drug utilization study in post-operative patients in obstetrics and gynecology ward of a tertiary care teaching hospital

Cited by 5 publications

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A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

A Drug Utilization Study of Antimicrobials in Major Surgical Patients in Tertiary Care Teaching Hospital- A Prospective Observational Study

Observing Drug Utilization Trends of Analgesics in Indoor Surgical Patients in Tertiary Care Teaching Hospital

Prescribing pattern and WHO core prescribing indicators in post-operative patients of Gynaecology department of a Tertiary Care Teaching Hospital

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