Drug utilization pattern during pregnancy in Nekemte referral hospital: a cross sectional study

Abstract

<p class="abstract"><strong>Background:</strong> Pregnancy is a period of great physiological changes to the mother and fetus in which every malfunction of the body as the result of drug use may lead to serious consequences in both. It is a period that demands special care to the health care service providers. Therefore, the objective of this project is to conduct across sectional study on drug utilization pattern during pregnancy in Nekemte referral hospital, Ethiopia from 2012-2013 that could lay base for the maternal care programs.</p><p class="abstract"><strong>Methods:</strong> A purposive sampling was used to draw 100 pregnant women from the source population. Data were collected from the documented drug administration record of Nekemte referral hospital for all stages of pregnancy, types of drugs, roots of administration and dosage forms for all the pregnant female who were admitted to the hospital. </p><p class="abstract"><strong>Results:</strong> Among the pregnant women, who visited Nekemte referral hospital during the study period, the majority (96%) had a record for drug (s) and almost similar pattern of records were found in all wards for drug use. Of all the pregnant women, there was a high record for drug utilization of the women in the first trimester. Unemployed and uneducated pregnant females make the highest proportion. There was also a prescription of potentially dangerous drugs during pregnancy in Nekemte referral hospital.</p><p><strong>Conclusions:</strong> Many pregnant women were found using drugs during pregnancy in Nekemte referral hospital, including potentially harmful drugs. Therefore, there should be intensive assessment of pregnant women treatment in line with the US food and drug administration agency (FDA) risk category and locally operating regulations by considering risks and benefits to both mothers and the foetus in drug prescription and administration.</p>

Prescription drug use and potential teratogenicity risk among pregnant women attending maternal and child health clinic of Kemisse General Hospital, Northeast, Ethiopia

“…The prevalence of drug utilization in this study was found to be 88.97%, comparable with prevalence of 85.1% in eastern Ethiopia, Harar [11], 87.5% in northern Ethiopia [9] and 88.4% in north west Ethiopia, Bahirdar [12]. But this value is lower than a study in Nekemte (96%) [13].…”

Drug utilization pattern among pregnant women attending maternal and child health clinic of tertiary hospital in eastern Ethiopia: Consideration of toxicological perspectives

“…This value was comparable with the study conducted in northern Ethiopia [8] and Bahirdar city [12] where the prevalence of drug use during pregnancy was found to be 87.5% and 88.4%, respectively. With reference to this finding, lower and higher drug utilization were also reported in studies conducted at Ayder referral hospital, Mekele (62.2%) [16] and Nekemte town (96%) [17], respectively. Almost half of the drug used in the current finding was during the first trimester of pregnancy where the critical period of organogenesis lies and drug-induced teratogenicity is assumed to reach climax.…”

Patterns and determinants of prescribed drug use among pregnant women in Adigrat general hospital, northern Ethiopia: a cross-sectional study

“…In this study, the overall prevalence of consumption of medications among pregnant women was 87.7%. This finding is comparable to the 87.5% in Northern Ethiopia [19] 88.4% in Bahr Dar city [28], 85.1% in Harer [15], 85.2% in Germany [20], but lower than the 96% in Nekemte City [32], 93-99% in France [20] and 93% in Iceland [33]. Moreover, the prevalence was higher than 71.3% in Addis Ababa [29], 73.2% in Cameroon [34], 79.1% in Netherlands [23], 65% in United Kingdom [24], and 56% in Canada [20].…”