Drug use and risk behaviour profile, and the prevalence of HIV, hepatitis C and hepatitis B among people with methamphetamine use in Iran

Moradi, Ghobad; Hajarizadeh, Behzad; Rahmani, Khaled; Mohamadi-Bolbanabad, Amjad; Darvishi, Sonia; Zareie, Bushra; Zavareh, Fatemeh Azimian; Sharafi, Heidar; Alavian, Seyed Moayed; Ramazani, Rashid; Eftekhar, Mehrdad; Radfar, Seyed Ramin; Piroozi, Bakhtiar; Gouya, Mohammad-Mehdi

doi:10.1016/j.drugpo.2019.09.018

Cited by 19 publications

(13 citation statements)

References 22 publications

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“…Similar results were obtained in a cohort study funded by NIH/NIDA, indicating high prevalence of depression among HIV-infected MSM who were also meth users, compared to non-meth users, unemployed, as well as homeless participants [89]. A cross-sectional study performed in Iran highlighted the higher odds of emergence of viral infections, such as HIV and HCV, particularly among the meth users [90]. However, a Thai study reported a declined HIV incidence among people who inject drugs during 2005-2012 in a cohort from Bangkok.…”

Section: Incidence Of Methamphetamine Use Among Plwhasupporting

confidence: 78%

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

Desai

Burns

Gong

et al. 2020

Expert Opinion on Drug Metabolism & Toxicology

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Introduction: While considerable progress has been made in the fight against HIV/AIDS, to date there has not been a cure, and millions of people around the world are currently living with HIV/ AIDS. eople living with HIV/AIDS have substance abuse disorders at higher rates than noninfected individuals, which puts them at an increased risk of drug drug interactions.Areas covered: Potential drug drug interactions are reviewed for a variety of potential drugs of abuse, both licit and illicit. These drugs include alcohol, cigarettes or other nicotine delivery systems, methamphetamine, cocaine, opioids, and marijuana. Potential interactions include decreased adherence, modulation of drug transporters, or modulation of metabolic enzymes. We also review the relative incidence of the use of these drugs of abuse in People living with HIV/ AIDS.Expert opinion: Despite considerable improvements in outcomes, disparities in outcomes between PLWHA who use drugs of abuse, vs those who do not still exist. It is of critical necessity to improve outcomes in these patients, and to work with them to stop abusing drugs of abuse.

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Section: Incidence Of Methamphetamine Use Among Plwhasupporting

confidence: 78%

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

Desai

Burns

Gong

et al. 2020

Expert Opinion on Drug Metabolism & Toxicology

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“…The study on the homeless population in Tehran yielded a 6% prevalence of HIV in homeless MSM, similar to a study from 2009 that reported a 4.6% in the homeless from the same city ( 33 ). In the only study on people using methamphetamine as the emerging high-risk population, no HIV positive cases were detected ( 31 ).…”

Section: Discussionmentioning

confidence: 99%

HIV prevalence among men who have sex with men in Iran: A systematic review and meta-analysis

Ghalichi

Naserbakht

Ardebili

et al. 2021

Med. J. Islam. Republ. Iran

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“…Among survey participants, 41% reported injecting daily or more, and 39% had not been tested for HCV in the last 12-months. Methamphetamine was the most commonly reported last drug injected for survey participants (58%), indicating that outreach at ADMs provides opportunities for engaging with this group of PWID who may be at risk of HCV infection [ 31 , 32 ] but may not follow pathways into regular contact with face-to-face services in the way people who are opioid-dependent often do [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Setting foot in private spaces: extending the hepatitis C cascade of care to automatic needle/syringe dispensing machines, a mixed methods study

Coupland

Henderson²,

Pritchard-Jones

et al. 2022

Harm Reduct J

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Background Global commitment to achieving hepatitis C virus (HCV) elimination has enhanced efforts in improving access to direct-acting antiviral (DAA) treatments for people who inject drugs (PWID). Scale-up of efforts to engage hard-to-reach groups of PWID in HCV testing and treatment is crucial to success. Automatic needle/syringe dispensing machines (ADMs) have been used internationally to distribute sterile injecting equipment. ADMs are a unique harm reduction service, affording maximum anonymity to service users. This paper explores the feasibility and acceptability of extending the HCV cascade of care to sites where ADMs are located. Methods The ADM users into Treatment (ADMiT) study was undertaken in a metropolitan region in Sydney, Australia. This mixed methods study involved analysis of closed-circuit television footage, ethnographic methods (fieldwork observation and in-depth interviews) and structured surveys. Researchers and peers conducted fieldwork and data collection over 10 weeks at one ADM site, including offering access to HCV testing and treatment. Results Findings from 10 weeks of fieldwork observations, 70 survey participants and 15 interviews highlighted that there is scope for engaging with this population at the time they use the ADM, and enhanced linkage to HCV testing and treatment may be warranted. Most survey participants reported prior HCV testing, 61% in the last 12 months and 38% had received HCV treatment. However, fieldwork revealed that most people observed using the ADM were not willing to engage with the researchers. Field work data and interviews suggested that extending the HCV cascade of care to ADMs may encroach on what is a private space for many PWID, utilized specifically to avoid engagement. Discussion Enhanced linkage to HCV testing and treatment for people who use ADMs may be warranted. However, data suggested that extending the HCV cascade of care to ADMs may encroach on what is a private space for many PWID, utilized specifically to avoid engagement. The current study raises important public health questions about the need to ensure interventions reflect the needs of affected communities, including their right to remain anonymous.

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Drug use and risk behaviour profile, and the prevalence of HIV, hepatitis C and hepatitis B among people with methamphetamine use in Iran

Cited by 19 publications

References 22 publications

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

An update on drug–drug interactions between antiretroviral therapies and drugs of abuse in HIV systems

HIV prevalence among men who have sex with men in Iran: A systematic review and meta-analysis

Setting foot in private spaces: extending the hepatitis C cascade of care to automatic needle/syringe dispensing machines, a mixed methods study

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