Drug Therapy with Renal Failure

Bartges, Joe; Martı́n-Jiménez, Tomás

doi:10.1002/9781118785546.ch40

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S P E C I F I C T H E R a P E U T I C I S S U E S I N C A T ...1

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2016

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“…[179][180][181] Drugs that are primarily excreted in urine may accumulate in patients with CKD, leading to higher risks of adverse events; thus drugs primarily biotransformed by the liver or excreted by extrarenal routes (eg, benazepril, 182 telmisartan 183 ) are preferred where possible. Nevertheless, the risk:benefit ratio of each treatment should be assessed, 184 and dose adjustments may help to mitigate risks.…”

Section: S P E C I F I C T H E R a P E U T I C I S S U E S I N C A T ...mentioning

confidence: 99%

ISFM Consensus Guidelines on the Diagnosis and Management of Feline Chronic Kidney Disease

Sparkes¹,

Caney²,

Chalhoub

et al. 2016

Journal of Feline Medicine and Surgery

125

157

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In preparing these Guidelines, the Panel has carefully reviewed the existing published literature, and has also graded the quality of evidence for different interventions to help to provide practical recommendations on the therapeutic options for feline CKD. This is a field of veterinary medicine that has benefited from some excellent published clinical research and further research findings will undoubtedly modify the recommendations contained in these Guidelines in the future.

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