Drug Sensitivity of Bacteria Isolated by Blood Culture

Cronberg, S; Ericson, Carl; Skånsberg, Per

doi:10.3109/inf.1974.6.issue-3.07

Cited by 9 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gentamycin has the same general range of antibacterial activity as the other aminoglycosides, but has a higher degree of activity against Pseudornonas aencginosa and many E. coli, Proteus, Klebsiella and Staph. aureiis species, as compared with Kanamycin (7). Finally Gentamycin may have a lesser oto-and renal toxicity than kanamycin ( 15, 17, 22, 27), although no real comparison between the two drugs is available.…”

Section: Actu Pzdiirtr Sclrnd65mentioning

confidence: 99%

Septicaemia of the Newborn, Associated With Ruptured Foetal Membranes. Discoloured Amniotic Fluid or Maternal Fever

Knudsen

STEINRUD

1976

Acta Paediatrica

View full text Add to dashboard Cite

Abstract. The incidence of neonatal septicaemia associated with prolonged rupture of foetal membranes, discoloured amniotic fluid and/or maternal fever was investigated. A total of 807 blood cultures were performed on 329 neonates, the placental end of 239 umbilical cords and on 239 mothers. The study showed that in 97% of the neonates with a complicated delivery there was no evidence of septicaemia. Septicaemia was verified in 3% of the infants, and was intimately associated with low birth weight (p=0.02), neonatal asphyxia (p<10‐4), clinical evidence of septicaemia (p<10‐4) and maternal fever (p=0.002). The incidence was particularly high in premature infants with neonatal asphyxia (27%) and in neonates born to febrile mothers (20%). None of the mothers showed any evidence of septicaemia, and haematogenous, transplacental spread of infection to the child was not seen. Routine prophylactic antibiotic therapy in neonates with a complicated delivery should therefore be reserved, in our opinion, for those infants at high risk of infection.

show abstract

Section: Actu Pzdiirtr Sclrnd65mentioning

confidence: 99%

Septicaemia of the Newborn, Associated With Ruptured Foetal Membranes. Discoloured Amniotic Fluid or Maternal Fever

Knudsen

STEINRUD

1976

Acta Paediatrica

View full text Add to dashboard Cite

show abstract

“…Unfortunately no atoxic antibiotic is of any value against septicaemia caused by Gramnegative rods, which still are very important in newborn infants (2, 29). Therefore we have used Kanamycin although at present Gentamycin may be the drug of choice (7,22,23). It seems wise to combine the initial treatment by an aminoglycoside with ampicillin or penicillin G , since the former drugs are relatively inactive against streptococci.…”

Section: In Previous Investigationsmentioning

confidence: 99%

“…coli, Proteus, Klebsiella and Staph. aureus species, as compared with Kanamycin (7). Finally Gentamycin may have a lesser oto-and renal toxicity than kanamycin (15,17,22,27), although no real comparison between the two drugs is available.…”

Section: In Previous Investigationsmentioning

confidence: 99%

Septicaemia of Hte Newborn, Associated With Ruptured Foeral Mebbranes, Discoloured Amniotic Fluid or Maternal Fever

KUNDSEN¹,

STEINRUD²

1976

Acta Paediatrica

View full text Add to dashboard Cite

ABSTRACT. The incidence of neonatal septicaemia associated with prolonged rupture of foetal membranes, discoloured amniotic fluid and/or maternal fever was investigated. A total of 807 blood cultures were performed on 329 neonates, the placental end of 239 umbilical cords and on 239 mothers. The study showed that in 97% of the neonates with a complicated delivery there was no evidence of septicaemia. Septicaemia was verified in 3% of the infants, and was intimately associated with low birth weight (p = 0.02), neonatal asphyxia (p < 10‐4) clinical evidence of septicaemia (p < 10‐4) and maternal fever(p = 0.002). The incidence was particularly high in premature infants with neonatal asphyxia (27%) and in neonates born to febrile mothers (20%). None of the mothers showed any evidence of septicaemia, and haematogenous, transplacental spread of infection to the child was not seen. Routine prophylactic antibiotic therapy in neonates with a complicated delivery should therefore be reserved, in our opinion, for those infants at high risk of infection.

show abstract

Bacteremia in a swedish university hospital: A one-year prospective study in 1981 and a comparison with 1975–76

Ljungman¹,

Malmborg²,

Nyström³

et al. 1984

Infection

View full text Add to dashboard Cite

A one-year prospective study of bacteremia was carried out at a Swedish university hospital. Blood cultures were taken in 6.3% of all patients admitted to the hospital. 148 episodes of bacteremia were recorded in 142 patients, 59% of whom were males. The mean incidence of bacteremia was 4.3 episodes per 1,000 admissions. The incidence of contamination was 1.3%. Malignancy and urinary tract disorders were the most common diagnoses and surgical intervention, central venous catheters and cytostatic drugs the most common predisposing factors. The ratio of hospital to community-acquired bacteremia was 1.3:1. The fatality rate was 12.7%. Gram-negative rods belonging to the Enterobacteriaceae were the most common pathogens, followed by Staphylococcus aureus and Staphylococcus epidermidis. The antibiotic sensitivity pattern of the causative bacteria was quite favorable. No S. aureus strains were resistant to isoxazolyl penicillins or gentamicin. No Klebsiella strain and only one Escherichia coli strain was resistant to gentamicin. The results were compared to a one-year retrospective study carried out in the same hospital five years ago. The incidence of bacteremia had not increased between the two studies.

show abstract

Drug Sensitivity of Bacteria Isolated by Blood Culture

Cited by 9 publications

References 11 publications

Septicaemia of the Newborn, Associated With Ruptured Foetal Membranes. Discoloured Amniotic Fluid or Maternal Fever

Septicaemia of the Newborn, Associated With Ruptured Foetal Membranes. Discoloured Amniotic Fluid or Maternal Fever

Septicaemia of Hte Newborn, Associated With Ruptured Foeral Mebbranes, Discoloured Amniotic Fluid or Maternal Fever

Bacteremia in a swedish university hospital: A one-year prospective study in 1981 and a comparison with 1975–76

Contact Info

Product

Resources

About