Drug safety - important to us all!

Assessing the benefit-harm balance at the bedside

“…Drug safety researchers must now move beyond their traditional focus on the detection of adverse reactions and face the new hurdles of characterising known reactions in greater detail. After all, Bottiger argues that most deaths related to adverse reactions are not from rare, new, or unexpected complications but are due to well recognised reactions 9. We would be able to manage these adverse reactions better if we had information on their frequency, dose responsiveness, time course, and patients' susceptibility factors 10.…”