Drug resistant tuberculosis in prisons in Azerbaijan: case study

Abstract

Objectives: To document the existence of drug resistance in a tuberculosis treatment programme that adheres strictly to the DOTS principles (directly observed treatment, short course) and to determine the extent of drug resistance in a prison setting in one of the republics of the former Soviet Union.

Drug-Resistant Tuberculosis, KwaZulu-Natal, South Africa, 2001–2007

“…206 Studies later revealed that these patients were suffering from drug-resistant disease. 207,208 DOTS was adopted as the national strategy by the Ministry of Health in 2005, after which the country reported 100 percent coverage. Despite this coverage, treatment success rates among DOTS patients were quite low because of increasing drug resistance.…”

Schneller Nachweis von Mutationen im gyrA-Gen von Mycobacterium tuberculosis mit Relevanz für die Entstehung von Medikamentenresistenzen gegen Chinolone mittels der Real-Time PCR auf dem LightCycler® System

“…im Tomsk Oblast (Russland) von 6,5% (1998) auf 13,7% (2002). Eine besonders hohe Prävalenz der multiresistenten Tuberkulose findet sich vor allem bei osteuropäischen Gefängnisinsassen (Coninx, Pfyffer et al 1998). Da die tuberkuloseerkrankten Insassen häufig nicht vollständig kuriert entlassen werden, tragen diese erheblich zu der Weiterverbreitung von…”

TB Control in Prisons

“…At the same time, the average age of TB patients declined, reflecting high levels of recent transmission. From the 1990s onward, a growing number of studies reported the high burdens of TB, in particular MDR-TB, in prisoners in the former USSR Republics (Drobniewski 1995 ;Drobniewski et al 1996;Conninx et al 1998;Kimerling et al 1999;Aerts et al 2000). Although there is in recent year a tendency towards a reduction in TB incidence among prison inmates, a higher proportion of TB patients among prisoners have MDR strains than in patients outside prison.…”