Drug Resistant Tuberculosis and its Survielance

Insights on Blood Cytokines Production under Different <i>In Vitro</i> Mycobacterial Antigens in Tuberculosis Intestinal Parasites Co Infected Patients

“…The IL-8, or CXC chemokine, an important neutrophil-activating factor, provides the chemotaxis of inflammatory cells to the site of infection [1] and pretreatment with IL-8 inhibit granuloma formation. Among the pro-inflammatory cytokines assayed in our study, the IL-8 was the only one significantly up-modulated in IPTB, although without significance as compared to TB, but associated to 38 kDa/CFP-10 stimuli.…”

“…Mycobacterium tuberculosis (Mtb) is a facultative intracellular pathogen whose host immune response plays a vital role in infection outcome. The immune control of this infection is dependent upon the cellular immune response, mediated predominantly by CD4+ and CD8+ cells, with T helper (Th) 1 cytokine production, as IFN-γ, the major component in stimulation/activation of macrophages in infection control and bacillus elimination [1].…”