“…Tetraethyl silicate (TEOS), triethanolamine (TEA), 5,10,15,20-tetraphenylporphyrin (TPP), (5,10,15,20)tetra(4-aminophenyl)porphyrin (NH 2 -TPP), dextran and doxorubicin hydrochloride (DOX•HCl) were all purchased from Shanghai Aladdin Biochemical Technology Co., Ltd. 3-Aminopropyltrimethoxysilane (APS) was purchased from Braunwell Chemical Technology Co., Ltd. CA4P was acquired from Solarbio Science & Technology Co., Ltd. Cetyltrimethylammonium chloride (CTAC) was purchased from Sigma-Aldrich Co., Ltd. Dulbecco's modi ed Eagle's medium (DMEM), memorial institute medium (RPMI)-1640, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), 4',6-diamidino-2-phenylindole (DAPI), 1,3-diphenylisobenzofuran (DPBF), 2',7'-dichlorodihydro uorescein diacetate (DCFH-DA), live/dead cell viability/toxicity kit, and Annexin V-FITC/PI staining kit were all purchased from Vicmed (Xuzhou, China). Caspase 3 polyclonal antibody (caspase 3 PAb) was purchased from Proteintech Co. (USA).…”