Rook's Textbook of Dermatology 2004
DOI: 10.1002/9780470750520.ch73
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Drug Reactions

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Cited by 41 publications
(60 citation statements)
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References 2,776 publications
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“…Most of the adverse effects of D-penicillamine are cutaneous and they occurring in 25∼50% of patients. These adverse effects can be classified into three groups 3 , including early onset morbilliform and urticarial hypersensitivity reactions and later onset bullous and lupus-like autoimmune reactions 9 . The third group of dermopathies is a spectrum of cutaneous elastotic and collagen disorders 3 such as PXE, EPS, cutis laxa and anectoderma 4,5 .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Most of the adverse effects of D-penicillamine are cutaneous and they occurring in 25∼50% of patients. These adverse effects can be classified into three groups 3 , including early onset morbilliform and urticarial hypersensitivity reactions and later onset bullous and lupus-like autoimmune reactions 9 . The third group of dermopathies is a spectrum of cutaneous elastotic and collagen disorders 3 such as PXE, EPS, cutis laxa and anectoderma 4,5 .…”
Section: Discussionmentioning
confidence: 99%
“…hypersensitivity reactions, autoimmune conditions and a spectrum of cutaneous elastotic and collagen disorders 3 .…”
Section: Introductionmentioning
confidence: 99%
“…The blood neutrophil count is usually elevated, and mild renal impairment occurs in approximately 30% of the cases; both of these abnormalities disappear with improvement of the eruption 1 . Other lesions that may be seen in patients with this dermatosis are erythema multiforme-like target lesions, vesicles, blisters or purpura 3 . Mucous membrane involvement, if it occurs, is generally mild and limited to one location.…”
Section: Discusstionmentioning
confidence: 98%
“…The bacteriological and fungal examinations of the pustules are negative. In most patients the rash often develops within 24∼48 h of drug exposure on the face or in the flexures, and then it rapidly disseminates and lasts about 1∼2 weeks 1,3 . In addition, the EuroSCAR study observed 2 different patterns for the onset time after exposure to the offending agent.…”
Section: Discusstionmentioning
confidence: 99%
“…BE have been described with barbiturates, methadone, imipramine, and glutethimide overdoses. 1 Among the benzodiazepines, nitrazepam, 2 diazepam, 3 and oxazepam 4 have been associated with BE. We describe an 83-year-old woman presenting with coma and BE after an overdose with temazepam.…”
mentioning
confidence: 99%