Drug reaction with eosinophilia and systemic symptoms (DRESS) induced by phenytoin re-exposure: case report and systematic review

DRESS and Stevens–Johnson Syndrome Overlap Secondary to Allopurinol in a 50-Year-Old Man—A Diagnostic and Treatment Challenge: Case Report

“…DRESS syndrome is characterized by cutaneous and hematological manifestations with multisystemic involvement. Symptoms usually start between 2 and 90 days with an average of 23 days after consumption of the causative drug [12]. It usually involves a prodromal period characterized by fever, lymphadenopathy, pruritus, and flu-like symptoms [9].…”

Screening the European pharmacovigilance database for reports of clozapine-related DRESS syndrome: 47 novel cases

“…The demographic characteristics of our sample reflect average characteristics of patients with treatment-resistant schizophrenia that are usually prescribed clozapine (de Filippis et al, 2021b). The larger number of males with clozapine-related DRESS most likely reflects the more frequent prescription of clozapine in males rather than females (Cacoub et al, 2011;Morán-Mariños et al, 2022). Interestingly, we found a male to female ratio of 1.3:1 for DRESS, which is only a bit lower than the 1.4:1 ratio reported for schizophrenia (Jongsma et al, 2019), thus confirming the overall overlapping trend between our findings and schizophrenia diagnosis and treatment epidemiology.…”

Proposed algorithm to recover anti-tuberculosis drugs that cause drug reaction with eosinophilia and systemic symptoms (DRESS)

“…Se describen que los anticonvulsivantes, alopurinol y antibióticos son la causa más frecuente del síndrome de DRESS (2) . La aparición suele ser entre dos y ocho semanas después de la primera exposición.…”