Drug prescribing pattern at the medical outpatient clinic of a tertiary hospital in southwestern Nigeria

Enwere, Okezie Oguamanam; Falade, Catherine O.; Salako, Babatunde Lawal

doi:10.1002/pds.1475

Cited by 51 publications

(54 citation statements)

References 12 publications

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“…This value correlates with a previous study 9 carried out in Ibadan, which reported the average number of drugs prescribed as 3.2.…”

Section: Discussionsupporting

confidence: 91%

Patterns of Drug Use and Adherence in the Management of Hypertension in a Health Care Facility in Warri, Delta State, Nigeria

Erah

et al. 2015

PBJ

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Hypertension is one of the treatable causes of cardiovascular morbidity and mortality.Management and evaluation of hypertension helps to streamline treatment protocols in hospitals that conform to global practice standards. Critical to hypertension management is adherence and lack of knowledge to adhering to prescribed medications may constitute treatment failure. To determine the patterns and adherence level of antihypertensives and impacting factors to nonadherence.The case files of adult hypertensive patients of the Central hospital Warri that were surveyed for a period of six months was 400 for drug use pattern. Reasons for non-adherence was also gathered. The 8-item Morisky questionnaire was used to gather information on adherence. Females affected was 69.8% with mean systolic blood pressure (SBP) of 153.3mmHg±16.7 and males 30.2% with mean systolic blood pressure (SBP) of 155.3mmHg±17.3% and mean diastolic blood pressure (DBP) for females (91.8mmHg±10.7) and males (92.0mmHg±9.8). After the start of therapy, mean SBP and DBP for females (143.8mmHg±22.3; 86.4mmHg±12.5) and males (143.6mmHg±22.1; 87.9mmHg±11.6). The most frequently prescribed antihypertensive was calcium channel blockers (29.7%) and next was angiotensin converting enzyme inhibitors (24.8%) and these were the commonest multitherapy (50%) encountered. Adherence level was 84%. Reasons for non-adherence were affordability and forgetfulness to take medications. Calcium-channel blockers and angiotensin converting enzyme inhibitors were mostly prescribed, and as dual therapy while diuretics were rarely used.Adherence to medication was relatively high, but their blood pressure was poorly controlled.Reasons for non-adherence were the inability of respondents to afford medications and forgetfulness.

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“…This value correlates with a previous study 9 carried out in Ibadan, which reported the average number of drugs prescribed as 3.2.…”

Section: Discussionsupporting

confidence: 91%

Patterns of Drug Use and Adherence in the Management of Hypertension in a Health Care Facility in Warri, Delta State, Nigeria

Erah

et al. 2015

PBJ

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“…The low percentage prescription of drugs by their generic name is responsible for the high cost of drugs to patients. Our value is less than that reported in other studies which were 23.6 and 80% drugs were prescribed from essential drugs list (Enwere et al, 2007). Drug use studies are a necessary tool for assessing prescribing problems in hospitals, recognizing areas for improvement and improving drug prescribing practices in these facilities (Bharity et al, 2008).…”

Section: Discussionmentioning

confidence: 59%

Assessment of antibiotic prescribing behavior of consultants of different localities of Pakistan

Riaz¹,

Malik²,

Raza³

et al. 2011

Afr. J. Pharm. Pharmacol.

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The objective of study was to evaluate the pattern and practice of consultants especially antimicrobials in the allopathic health sector in Pakistan to assess the magnitude of the problem and suggesting corrective measures. A cross-sectional survey in various cities of Pakistan was conducted which was developed in line with WHO and has so far been implemented in 12 developing countries. A total of 4923 prescriptions of 197 consultants were collected and analyzed. Drugs dispensed were 480142; average number of drugs per prescription for all disciplines was 3.13±1.5. The number of encounters with antibiotics in medicine department was 20.17% of the total antibiotic while ophthalmology had no encounter with injectables. Cost of 23.79% of prescriptions was below Rs.100 and 4.9% above 500 rupees. Therapeutic categories of the drugs prescribed were 14.6% antimicrobial followed by 12.5% cardiovascular or renal drugs. The age of the patient, severity of disease, socio-economic status, previous experience of treating similar patients were important factors that determined choice of drugs. EDL was not available in most of the facilities. Around 80% drugs were prescribed by brand name. The drugs prescribed from the essential list were around 30%. Concern of losing patients to others practitioners was considered among the top three factors by only 18% of providers. Age of the patient, severity of disease, socio-economic factors were important factors that determined choice of drugs. Prescribing and dispensing practices are inappropriate and irrational in Pakistan like many developing countries. Managerial and regulatory interventions are proposed to improve the rational use of drugs.

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“…Recently, there has been a rigorous effort to ensure RUD for which WHO has identified specific drug use indicators that include number and cost of drugs, use of generic names in prescribed drugs and adherence to Essential Drug List (EDL). 15 Gender analysis showed higher number of male patients [187{62%}] than female [113{38%}. As mentioned by previous researcher in Malaysia, the frequency of prescriptions for cardiovascular drugs for men was higher than that for women.…”

Section: Resultsmentioning

confidence: 94%

Patterns of Drug Utilization in Cardiology Department of a Tertiary Level Hospital in Bangladesh

Afroj

Parveen

Ara³

et al. 2014

Bangladesh J Physiol Pharmacol

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A cross-sectional descriptive study was carried out among patients admitted in cardiology department from 1 st January to 31 st March 2011 in Sir Salimullah Medical College & Mitford Hospital, Dhaka to see the patterns of prescriptions and use of drug by using WHO core drug use indicators and some additional indices. A total of 300 patients were included in this study .The average number of drugs per encounter was 8.8 and 11.43% drugs were prescribed by generic name. Percentage of encounters with cardiovascular drugs were 64%,other drugs were 36% and 25% injection were prescribed.70.45% drugs were prescribed from EDL of Bangladesh, the availability of copy of essential drug list was present and availability of key drugs was 74%.So the results of the present study may contribute to identify essential drug prescribing patterns in our country.

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Drug prescribing pattern at the medical outpatient clinic of a tertiary hospital in southwestern Nigeria

Cited by 51 publications

References 12 publications

Patterns of Drug Use and Adherence in the Management of Hypertension in a Health Care Facility in Warri, Delta State, Nigeria

Patterns of Drug Use and Adherence in the Management of Hypertension in a Health Care Facility in Warri, Delta State, Nigeria

Assessment of antibiotic prescribing behavior of consultants of different localities of Pakistan

Patterns of Drug Utilization in Cardiology Department of a Tertiary Level Hospital in Bangladesh

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