“…As Cox (2011) has suggested, the particular geographical formations of race, class, unemployment and opportunity cannot be considered apart from the larger landscape of American ideology and social policy. While abundant existing research supports the position that high levels of substance misuse and addiction are indicators of social exclusion and deprivation (Parker, Bakx & Newcombe, 1988; Fagan, 1992; Ensminger, Anthony, & McCord, 1997; Foster, 2000), it remains to be seen whether deliberate or efforts at altering that landscape--improving urban living conditions more generally (Freudenberg et al, 2005), building social inclusion at different scales (Smith, Bellaby & Lindsay, 2010), or redirecting metropolitan drug policy at broader social welfare, rather than control and enforcement (Kubler & Walti, 2001)--might mitigate either the causes or the effects of heroin use, in terms of overdose deaths, economic marginality, or associated criminal activities. Comparative research on cities or regions with markedly different histories and patterns of racial and spatial segregation, such as those of Latin America (Arias 2006; Sabatini & Salcedo 2011) might help to elucidate the relationship between ethnic or class-based ghettos and heroin distribution patterns, and illicit drug markets more generally.…”