Drug kinetics release from Eudragit – Tenofovir@SiOC tablets

Tamayo, Aitana; Mazo, M. Alejandra; Veiga, María-Dolores; Ruíz-Caro, Roberto; Notario-Pérez, Fernando; Rubio, Juan

doi:10.1016/j.msec.2017.03.016

Cited by 24 publications

(20 citation statements)

References 46 publications

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“…The test of bioactivity for the released antibiotic agent on the organism has been discussed in the literatures. 12,15,16 The method for the test in the study is the same with that reported by Chen et al (2012). 12 Here shows the brief description.…”

Section: Methodsmentioning

confidence: 72%

“…Similar approaches have been reported in the literature. 14,15 We prepared the phosphate buffer solution (pH 7.4, 25 mL) as the dissolution medium for the tests of drug release behaviour from the PLA disk. The PLA disks with surface modication were incubated in the phosphate buffer saline at the temperature of 37 C with the wavering rate of 30 rpm.…”

Section: Methodsmentioning

confidence: 99%

“…Detail discussion about these models can be obtained in the literature. [26][27][28][29] Fig . 3(I)-(IV) shows the tting results of samples (A)-(F) using the zero-order, rst order, Higuchi and Korsmeyer-Peppas models, respectively.…”

Section: Methodsmentioning

confidence: 99%

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Long-term antibacterial performances of biodegradable polylactic acid materials with direct absorption of antibiotic agents

et al. 2018

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Section: Methodsmentioning

confidence: 72%

Section: Methodsmentioning

confidence: 99%

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Long-term antibacterial performances of biodegradable polylactic acid materials with direct absorption of antibiotic agents

et al. 2018

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“…Grossenbacher et al [148] demonstrated that the polymer-derived ceramics were stable and low toxicity, and their electrical conductivity could be adjusted by carbon doping, which could be used in implantable electrode applications such as pacemakers. Tamayo et al [149][150][151] fabricated mesoporous SiOC for controlled drug delivery. A mixture of organosilicon sol was prepared and aged to form gel by the addition of NH 4 OH solution, which transferred into SiOC after pyrolysis at 1100 ℃.…”

Section: Wwwspringercom/journal/40145mentioning

confidence: 99%

“…Silicon carbonitride (SiCN) derived from polysilazane possesses the outstanding properties including thermal stability, high mechanical strength, and excellent fracture toughness, which shows great potential for high temperature and structure applications [153,154]. In general, amorphous SiCN ceramics can be obtained at 1000 ℃, which are transferred into SiC and Si 3 N 4 phases with free carbon at a higher temperature, and then β-SiC could be formed from the reaction between Si 3 N 4 and free carbon over 1800 ℃ [73,[147][148][149][150].…”

Section: Wwwspringercom/journal/40145mentioning

confidence: 99%

Organosilicon polymer-derived ceramics: An overview

Zhu

2019

J Adv Ceram

141

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Polymer-derived ceramics (PDCs) strategy shows a great deal of advantages for the fabrication of advanced ceramics. Organosilicon polymers facilitate the shaping process and different silicon-based ceramics with controllable components can be fabricated by modifying organosilicon polymers or adding fillers. It is worth noting that silicate ceramics can also be fabricated from organosilicon polymers by the introduction of active fillers, which could react with the produced silica during pyrolysis. The organosilicon polymer-derived ceramics show many unique properties, which have attracted many attentions in various fields. This review summarizes the typical organosilicon polymers and the processing of organosilicon polymers to fabricate silicon-based ceramics, especially highlights the three-dimensional (3D) printing technique for shaping the organosilicon polymerderived ceramics, which makes the possibility to fabricate silicon-based ceramics with complex structure. More importantly, the recent studies on fabricating typical non-oxide and silicate ceramics derived from organosilicon polymers and their biomedical applications are highlighted.

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Kinetic Modeling to Explain the Release of Medicine from Drug Delivery Systems

Askarizadeh,

Esfandiari,

Honarvar

et al. 2023

ChemBioEng Reviews

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Proper medication dissolution must be ensured when developing or manufacturing a new solid dosage form. Quantitative analyses performed in dissolution or release tests become simpler when applying mathematical formulae which represent dissolution outcomes as a function of several dosage form properties. Methodologies utilized to examine the kinetics of drug release from controlled‐release formulations are reviewed. The analysis of variance was conducted using statistical, model‐independent, and ‐dependent techniques for the dissolution profile comparison and fitting, respectively. Model equations, including zero‐ and first‐order, Hixson‐Crowell, Weibull, Higuchi, Korsmeyer‐Peppas, Baker‐Lonsdale, Hopfenberg, etc., were employed to match the experimental data. Additional release parameters were taken to illustrate the drug release patterns. Using correlation factors and the Akaike information criterion (AIC), the best‐fitting model was discovered, as were the transport phenomena affecting the behavior of the recognized formulations.

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Drug kinetics release from Eudragit – Tenofovir@SiOC tablets

Cited by 24 publications

References 46 publications

Long-term antibacterial performances of biodegradable polylactic acid materials with direct absorption of antibiotic agents

Long-term antibacterial performances of biodegradable polylactic acid materials with direct absorption of antibiotic agents

Organosilicon polymer-derived ceramics: An overview

Kinetic Modeling to Explain the Release of Medicine from Drug Delivery Systems

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