Drug Interactions with Garlic and Ginger Supplements

Abou‐Diwan, Charbel; Ritchie, James C.

doi:10.1002/9780470910108.ch16

Cited by 2 publications

(1 citation statement)

References 112 publications

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“…Future studies should validate the effectiveness of TMs, and determine potential pharmacokinetic interactions when TMs are taken alongside CMs [15]. Some common herbal medications such as garlic and ginger are known to interact with conventional treatments leading to reduced clearance and raised plasma concentrations [35,36]. Rifampicin is a known inducer of CYP450 enzymes and p-glycoprotein, and hence the risk of adverse drug-herb interactions could potentially lead to serious toxicity in patients [37,38].…”

Section: Tmps As Healthcare Providers In Tb Treatmentmentioning

confidence: 99%

The Practice and Modalities of African Traditional Medicine in Tuberculosis Treatment - A Traditional Medical Practitioners’ Perspective

Chipato,

Mandishona,

Mbera

et al. 2024

J. Compl. Altern. Med. Res.

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Aims: This study sought to explore the role of the traditional medical practitioner (TMP) and document the modalities of tuberculosis (TB) treatment in traditional medicine (TM) in Harare, Zimbabwe. Study design: An ethnographic research survey of TMPs in Harare urban. Place and Duration of Study: Harare’s southern suburbs of Warren Park, Mufakose, Budiriro, Belvedere, Mbare (Mupedzanhamo) and Harare central business district, between April and June 2021. Methodology: Fourteen (14) experienced TB practitioners, registered with the Zimbabwe National Traditional Healers Association (ZINATHA) were recruited for the study. These included exclusive herbalists (36%), spiritualists (14%) and those who used a combination of spiritualism and herbalism (50%) in their practice. Data was collected through semi-structured in-person interviews. The practices and treatment modalities in the traditional treatment of TB were documented; and any linkages with the conventional medical system were identified. Results: Forty-six (46) plant species from 28 families were prescribed in various polyherbal combinations for a maximum of 6 months in difficult cases. TMPs were found to be relevant and knowledgeable in the treatment of TB. In addition to offering alternative or complementary treatment options to patients, TMPs were also agents of health education promotion, and collaborated to some extent with allopathic healthcare providers across the service delivery system from diagnosis to treatment of patients. Conclusion: If formalized, TMPs have the potential to make considerable contributions to TB treatment strategies and help improve treatment outcome in TB patients.

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Section: Tmps As Healthcare Providers In Tb Treatmentmentioning

confidence: 99%

The Practice and Modalities of African Traditional Medicine in Tuberculosis Treatment - A Traditional Medical Practitioners’ Perspective

Chipato,

Mandishona,

Mbera

et al. 2024

J. Compl. Altern. Med. Res.

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Drug-Herb Interactions among Thai Herbs and Anticancer Drugs: A Scoping Review

et al. 2022

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More than half of Thai patients with cancer take herbal preparations while receiving anticancer therapy. There is no systematic or scoping review on interactions between anticancer drugs and Thai herbs, although several research articles have that Thai herbs inhibit cytochrome P450 (CYP) or efflux transporter. Therefore, we gathered and integrated information related to the interactions between anticancer drugs and Thai herbs. Fifty-two anticancer drugs from the 2020 Thailand National List of Essential Medicines and 75 herbs from the 2020 Thai Herbal Pharmacopoeia were selected to determine potential anticancer drug–herb interactions. The pharmacological profiles of the selected anticancer drugs were reviewed and matched with the herbal pharmacological activities to determine possible interactions. A large number of potential anticancer drug–herb interactions were found; the majority involved CYP inhibition. Efflux transporter inhibition and enzyme induction were also found, which could interfere with the pharmacokinetic profiles of anticancer drugs. However, there is limited knowledge on the pharmacodynamic interactions between anticancer drugs and Thai herbs. Therefore, further research is warranted. Information regarding interactions between anticancer drugs and Thai herbs should provide as a useful resource to healthcare professionals in daily practice. It could enable the prediction of possible anticancer drug–herb interactions and could be used to optimize cancer therapy outcomes.

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Drug Interactions with Garlic and Ginger Supplements

Cited by 2 publications

References 112 publications

The Practice and Modalities of African Traditional Medicine in Tuberculosis Treatment - A Traditional Medical Practitioners’ Perspective

The Practice and Modalities of African Traditional Medicine in Tuberculosis Treatment - A Traditional Medical Practitioners’ Perspective

Drug-Herb Interactions among Thai Herbs and Anticancer Drugs: A Scoping Review

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