Drug eruptions in the elderly

Carneiro, Sueli Coelho da Silva; Azevedo-e-Silva, Melissa Chaves; Ramos‐e‐Silva, Márcia

doi:10.1016/j.clindermatol.2010.07.006

Cited by 26 publications

(23 citation statements)

References 28 publications

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“…Bu nedenle kreatinin klirensi normal olan yaşlılarda bile ilaç verilirken dikkat edilmelidir. 8,9 İleri yaşlarda ilaçların gastrointestinal sistemden difüzyonunda değişiklik olmamasına rağmen adipoz dokunun artması ve intraselüler ve ekstraselüler sıvının azalması, vücuttaki ilaç dağılımını etkiler. Yaşlılarda total vücut suyunun azalmasın-dan doğal nedenlerin dışında, sıkça kullanılan diü-retikler de sorumludur.…”

Section: Discussionunclassified

Cutaneous Drug Reactions and Causative Drugs in Patients Aged 55 Years and Over

Dilek¹,

Saral²,

Yüksel³

et al. 2013

Turkiye Klinikleri J Med Sci

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laç reaksiyonları; herhangi bir hastalığın önlenmesi, tedavisi veya teş-hisi için uygulanan ilacın neden olduğu zararlı veya istenmeyen etkilerdir. Hemen her klinikte görülen ilaç reaksiyonları, tüm hastaların were women and 47 were men. The ages of the patients ranged between 55 and 85 years (mean age 63.8±8.4). The most frequently detected cutaneous drug reactions were urticaria, angioedema, maculopapular drug eruptions, fixed drug eruptions and pruritus. Anti-inflammatory agents, analgesics and antipyretics, antihypertensives, antimicrobials and neuropsychiatric drugs were the most commonly implicated drugs. A history of chronic disease and continuous drug use was evident in 60.4% of patients. Antihypertensives were the most frequent agents causing cutaneous drug eruptions. A history of drug allergy was present in 15.3% of the cases. C Co on nc cl lu us si io on n: : Anti-inflammatory agents, analgesics, antipyretics, antihypertensives and antimicrobial drugs lead to cutaneous drug reactions most frequently in advanced ages. Urticaria, angioedema and maculopapular eruptions are the most common clinical forms. Antibiotics and chemotherapeutics were determined to cause severe cutaneous reactions such as generalized exanthematous pustulosis and erythroderma.

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Section: Discussionunclassified

Cutaneous Drug Reactions and Causative Drugs in Patients Aged 55 Years and Over

Dilek¹,

Saral²,

Yüksel³

et al. 2013

Turkiye Klinikleri J Med Sci

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“…Bozulmufl renal, kardiyak ve hepatik fonksiyonlar ilaç metabolizmas› ve etkileflimini etkiler. [22] Yafll›larda doz ile iliflkili ilaç yan etkileri idyosenkratik ilaç yan etkilerine göre daha yayg›nd›r.…”

Section: ‹Laç Erüpsiyonlar›unclassified

“…Melanom; özellikle yafll› erkeklerde genç yetiflkinlere oranla daha kal›n lezyonlar fleklinde ortaya ç›kar (Resim 13): Bu durum, di¤er medikal problemlerden, gözlem yetersizli¤inden ve derilerini uygun muayene etmemelerinTablo 5. ‹laçlar›n s›kl›kla neden oldu¤u klinik reaksiyonlar [22] Deri lezyonu Suçlanan ajanlar Tablo 6. Yafll›larda premalin, benin ve malign tümörlerlerin s›-n›fland›r›lmas› [23] Benin tümörler ve Malin tümörler premalin lezyonlar den kaynaklan›r.…”

Section: Deri Tümörleriunclassified

Common skin diseases of the elderly

Parlak¹,

Küçükuslu²,

Aydoğan³

2012

Turk Aile Hek Derg

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“…Polypharmacy causes an increase in the risk of side effects and interaction between medicines, treatment costs, hospitalization requirements, rates of incompatibility to medical treatment and resulting problems [11].…”

Section: Polypharmacymentioning

confidence: 99%

“…However, whether necessary or not, polypharmacy leads to the occurrence of some problems. The problems related to polypharmacy can be listed as side effects of the medicines, medicinemedicine interactions, increased medical expenses, medicine unconformities, increased hospitalization and medication mistakes [11].…”

Section: The Impact Of Polypharmacy On Oral and Dental Healthmentioning

confidence: 99%

Polypharmacy and Oral Health among the Elderly

Doğan¹

2016

JDODT

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Over the age of 65 populations is constantly increasing in the past 50 years. The elderly population is exploding. This is based on the fact that the living conditions of this population is improving, as well as individual and community health, and advances in sanitation. Elderly have the highest medication use in the world compared to other segments of the population. The goal of the medication use is to treat diseases and to make them feel better, which increases their quality of life. Over use of some medications has become a public health problem. Multiple drug use (Polypharmacy), causes an increase in the risk of side effects and interaction between drugs, treatment costs, hospitalization requirements, rates of incompatibility to medical treatment and resulting problems. The purpose of the scientific evidence of the literature can represent information and reviews based on polypharmacy during dental treatment to emphasize the importance of the recognition of the risks. As a result, periodontal disease, dental caries and xerostomia may be linked to complications associated with multiple drug use in the elderly.Keywords: Polypharmacy; Oral health; Dental caries; Oral diseases; Elderly population population accelerated. With the existing populationincrease projection it is estimated the world willbe home to 8.909 billion people in 2050. Due to the extension of life expectancy and decrease in birth rate, the world is aging more rapidly than the previous 50 years [2].Elderly population is constantly increasing in the past 50 years on a global scale. According to WHO, the number of people over the age of 65 will increase by 85% in the next 25 years, and working population will increase by 45 percent. As of 2015 901 million people are at the age of 60 or above, which makes 12% of the world population Figure 1. Over the age of 65 populations is increased by 3.26% on an annual basis. Over the age of 65 population is expected to reach 1.4 billion in 2030 and 2.1 billion in 2050 [3]. The most important reasons for this increase are the decrease in infant and child deaths, achievements in vaccination and health conditions and sustainability thereof as well as development of antibiotics. However, the fundamental factor is the decrease in mortality, not only in infants and children but in all age groups. Another reason is that people are exceeding the age of 65 which is life expectancy. For this reason, it is expected that welfare of elderly people will be found in the list of problems with priority in the areas with increase in the following years [4].With aging, deceleration and degeneration can be witnessed in system functions as a result of the changes in human body. Because of age or associated conditions, level of absorption, blood flow and emission of basal and stimulated stomach acid decreases in gastrointestinal system. Absorption can also be affected in the elderly as a result of using multiple medicines simultaneously. For example, congestive heart failure, which is one of the most frequently seen dise...

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Drug eruptions in the elderly

Cited by 26 publications

References 28 publications

Cutaneous Drug Reactions and Causative Drugs in Patients Aged 55 Years and Over

Cutaneous Drug Reactions and Causative Drugs in Patients Aged 55 Years and Over

Common skin diseases of the elderly

Polypharmacy and Oral Health among the Elderly

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