Drug-Eluting or Bare-Metal Stents for Acute Myocardial Infarction

Abstract

In patients presenting with acute myocardial infarction, treatment with drug-eluting stents is associated with decreased 2-year mortality rates and a reduction in the need for repeat revascularization procedures as compared with treatment with bare-metal stents.

2009 Focused Updates: ACC/AHA Guidelines for the Management of Patients With ST‐Elevation Myocardial Infarction (Updating the 2004 Guideline and 2007 Focused Update) and ACC/AHA/SCAI Guidelines on Percutaneous Coronary Intervention (Updating the 2005 Guideline and 2007 Focused Update)

“…110 Compared with balloon angioplasty, routine BMS implantation during primary PCI decreases risk for TVR and possibly reduces MI rates but does not reduce mortality rates. 111,112 Two-year data from the Massachusetts registry 113 from 1221 propensity score-matched pairs of DES and BMS patients demonstrated a reduction in mortality and TVR rates with DES in primary PCI, and an analysis from the New York State registry 114 found a reduction in mortality rates but not TVR rates with DES. These reports were limited to patients treated More recently, several relatively small randomized clinical trials have shown an inconsistent efficacy for DES over BMS in primary PCI.…”

Safety and efficacy of hybrid platform design sirolimus eluting stent system in percutaneous coronary intervention in ST elevation myocardial infarction patients at 1 year after treatment

“…Hence, outcomes of studies performed favoured use of Bare Metal Stent (BMS) over DES. 11,12 However, meta-analysis presented a different view of various drug eluting stents. 13 The Horizon AMI and Horizon -III studies have demonstrated that rates of MACE and stent thrombosis are similar in DES and BMS.…”

Comparison of Mid-term Angiographic and Clinical Outcomes Following Zotarolimus-eluting Stent and Paclitaxel-eluting Stent Implantation Based on Lesion Complexity

“…It is possible that there could be a relationship between the higher percentage of dialysis and lesion calci cation in the PES group. Secondly, several randomized studies have demonstrated the superiority of DESs over BMSs for the treatment of ACS 10 . However, during the era of rst-generation DESs, the use of DESs for ACS cases was debated due to the risk of late and very late stent thrombosis VLST [11][12][13] .…”