Drug-Eluting Balloons–A New Tool in the Treatment of Cardiac Allograft Vasculopathy: A Case Series

Škorić, Boško; Bulum, Joško; Čikeš, Maja; Jurin, Hrvoje; Lovrić, Daniel; Ljubas-Macek, Jana; Samardžić, Jure; Pašalić, Marijan; Miličić, Davor

doi:10.1016/j.transproceed.2017.06.010

Cited by 3 publications

(1 citation statement)

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“…Recently, drug-coated balloons (DCBs) have been successfully used for CAVs in adults. [ 3 - 5 ] Although some studies have reported on DCBs in children with pulmonary vein stenosis,[ 6 ] there are no reports on the use of DCBs in CAVs. We present the case of a pediatric patient with CAV who was treated by PCI using a DCB for severe stenosis following heart transplantation (HTx).…”

Section: Introductionmentioning

confidence: 99%

Use of drug-coated balloon instead of drug-eluting stent for pediatric cardiac allograft vasculopathy

Narita¹,

Hirose²,

Hashimoto³

et al. 2023

Ann Pediatr Card

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Cardiac allograft vasculopathy (CAV) sometimes leads to restenosis, even after percutaneous transcatheter intervention. Recently, drug-coated balloons (DCBs) have been successfully used to treat coronary artery disease, especially CAVs, in adults. However, no studies have used DCBs in pediatric CAVs. We encountered a patient with CAV who underwent cardiac transplantation for restrictive cardiomyopathy at the age of 2 years. Nine years after the transplantation, severe stenosis of the proximal left anterior descending branch was observed. Considering the patient’s young age and the possibility of restenosis, we performed an intervention with DCB. Follow-up conducted 7 months after the intervention showed no restenosis. Cardiac coronary artery lesions following transplantation are more likely to result in restenosis earlier than arteriosclerotic lesions. In pediatric patients, restenosis might require multiple stents and prolonged antiplatelet therapy. Our findings provide evidence supporting the possibility of an effective treatment of CAV in children.

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Section: Introductionmentioning

confidence: 99%