2021
DOI: 10.1055/a-1492-3293
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Drug-drug Interactions between COVID-19 Treatments and Antidepressants, Mood Stabilizers/Anticonvulsants, and Benzodiazepines: Integrated Evidence from 3 Databases

Abstract: Introduction The SARS-CoV-2 pandemic with psychiatric comorbidities leads to a scenario in which the use of psychotropic drugs may be required. This requires the support of evidence-based medicine to take into account possible interactions between antidepressants, mood stabilizers, benzodiazepines, and coronavirus infection treatments. Methods Three databases were consulted: (a) Lexicomp Drug Interactions, (b) Micromedex Solutions Drugs Interactions, (c)Liverpool Drug Interaction Group for COVID-19 therapies. … Show more

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Cited by 15 publications
(19 citation statements)
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References 47 publications
(59 reference statements)
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“…The standards of prescription improved after the intervention of the LPTs. The added difficulty of changes in specific treatments for COVID and its interactions with psychotropic drugs should be noted ( Plasencia-García et al, 2021 ). The challenge of implementing new treatment and follow-up programs, for example, for healthcare personnel, should also be considered.…”
Section: Discussionmentioning
confidence: 99%
“…The standards of prescription improved after the intervention of the LPTs. The added difficulty of changes in specific treatments for COVID and its interactions with psychotropic drugs should be noted ( Plasencia-García et al, 2021 ). The challenge of implementing new treatment and follow-up programs, for example, for healthcare personnel, should also be considered.…”
Section: Discussionmentioning
confidence: 99%
“…Lithium is contraindicated for concurrent use with hydroxychloroquine, chloroquine, and azithromycin. Anticonvulsants and benzodiazepines present little or no risk for adverse interaction with COVID-19 treatments [54].…”
Section: Pain Management In Covid-19mentioning
confidence: 99%
“…cardiovascular and metabolic disorders, coagulopathies, immunological disorders, etc. ), and possible drug interactions that can result in either reduced drug tolerance, efficacy or safety [43,44,75], caution should be paid when prescribing specific classes of drugs in psychiatric patients. Studies on drug safety and effectiveness in people with pre-existent mental disorders and using psychopharmacological treatments are required.…”
Section: Pharmacological Treatment Options For Covid-19 For People Wi...mentioning
confidence: 99%