Drug delivery using metal oxide nanoparticles

García, Mónica Cristina; Torres, J Hernando; Córdoba, Antonella V. Dan; Longhi, Marcela Raquel; Uberman, Paula M.

doi:10.1016/b978-0-12-823033-6.00029-6

Cited by 5 publications

(3 citation statements)

References 207 publications

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“…Metal oxide NPs were potential drug delivery systems. The moderate/low cytotoxicity of Ag 2 O/Ag NPs makes them a perfect candidate for drug delivery systems [154][155][156]. Ag 2 O/Ag NPs can be used in anticancer and antiviral therapy [157][158][159].…”

Section: Cytotoxicity To Human Cellsmentioning

confidence: 99%

Ag2O Nanoparticles as a Candidate for Antimicrobial Compounds of the New Generation

et al. 2022

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Antibiotic resistance in microorganisms is an important problem of modern medicine which can be solved by searching for antimicrobial preparations of the new generation. Nanoparticles (NPs) of metals and their oxides are the most promising candidates for the role of such preparations. In the last few years, the number of studies devoted to the antimicrobial properties of silver oxide NPs have been actively growing. Although the total number of such studies is still not very high, it is quickly increasing. Advantages of silver oxide NPs are the relative easiness of production, low cost, high antibacterial and antifungal activities and low cytotoxicity to eukaryotic cells. This review intends to provide readers with the latest information about the antimicrobial properties of silver oxide NPs: sensitive organisms, mechanisms of action on microorganisms and further prospects for improving the antimicrobial properties.

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Section: Cytotoxicity To Human Cellsmentioning

confidence: 99%

Ag2O Nanoparticles as a Candidate for Antimicrobial Compounds of the New Generation

et al. 2022

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“…Scientists have fabricated and examined various nanomaterials, but those based on metal oxide NPs have captured their interest due to distinct features. Numerous biomedical applications, such as bioimaging, medication and gene delivery, antioxidant therapy, photodynamic therapy (PDT), dentistry, hyperthermia treatments, and wound healing, have all been investigated with metal oxide NPs [ 132 ]. Zinc oxide (ZnO) spherical NPs have recently drawn considerable focus in biomedical domains as an anti-tumor agent.…”

Section: Inorganic Nanocarriersmentioning

confidence: 99%

Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

WADHWA,

CHAUHAN,

KUMAR

et al. 2024

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Background Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases, for example, PubMed, Science Direct, Google Scholar, and others, using specific keyword combinations, including “glioblastoma,” “brain tumor,” “nanocarriers,” and several others. Conclusion This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM management. Elucidation of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.

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“…Nowadays metal oxide nanoparticles are enormously used in different applications such electronics, [15] cosmetics, [16] catalysis, [17] storage devices, [18] drug delivery, [19] medicine, [20] and biomedical. [21] Transition metal based metallic oxide has become the emerging class and gained much attention of scientist and researchers.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in morphologically controlled synthesis of graphene oxide‐based nanocomposite as catalyst and fuel additive

Shahbaz

Jamil

Bibi

et al. 2022

J of Physical Organic Chem

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Nanocomposites become very important because of their reduce size (1–100 nm), large surface area, excellent optical magnetic, and electrical and mechanical properties. In many applications, graphene oxide‐based metallic nanocomposites emerged as an outstanding class of nanomaterials that are used for different applications. (GO‐ZnO) nanocomposite has gained more importance in recent years. The present research study is designed to synthesize nanocomposites and aims to monitor its characteristics and applications. Graphene oxide is synthesized by Hummers' method. Metal salts are used as precursor source of respective metal oxides. Wet chemical synthesis method such as solvothermal/hydrothermal and copreciptation processes is used because of its low cost and easy applications as compared with other processes used in the past, which have been costly and difficult to handle. Scanning electron microscopy (SEM) and X‐ray diffraction (XRD) techniques are used to discriminate GO‐Zinc oxide metallic nanocomposites. XRD is used to investigate the crystal structure, and SEM images showed that the synthesized GO/ZnO nanocomposites is irregular in shape with merged surfaces and the size is 100 nm−1 μm. The dark and light color shows hollow morphology of the nanocomposites, and particles are merged with each other and irregular in shape. The obtained data are statistically analyzed by using regression analysis for the further interpretations. VESTA, MATCH, Origin pro is used for the interpretation of XRD results of synthesized nanocomposites. Applications of metallic (GO/Zn) nanocomposite as catalytic activity and colorimetry, flash point, fire point, cloud point, pour point, specific gravity, and viscosity and for the degradation of Drimarene Red K‐4BL is performed.

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Drug delivery using metal oxide nanoparticles

Cited by 5 publications

References 207 publications

Ag2O Nanoparticles as a Candidate for Antimicrobial Compounds of the New Generation

Ag2O Nanoparticles as a Candidate for Antimicrobial Compounds of the New Generation

Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

Recent advances in morphologically controlled synthesis of graphene oxide‐based nanocomposite as catalyst and fuel additive

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