Drug Abuse-Induced Cardiac Arrhythmias: Mechanisms and Management

Ouali, Sana; Guermazi, Omar; Guermazi, F.; Halima, M. Ben; Boudiche, Sélim; Khedher, Nadim; Meghaieth, Fathia; AbdeljalilFarhati,; Larbi, N.; Mourali, Mohamed Sami

doi:10.5772/intechopen.76022

Cited by 3 publications

(3 citation statements)

References 69 publications

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“…This patient was noted to have significant hepatic and renal injury, similar to our patient. Life threatening arrhythmias including ventricular fibrillation causing sudden cardiac death has been reported previously[ 6 - 8 ]. Toxic myopericarditis have been previously diagnosed in these patients[ 2 ].…”

Section: Discussionmentioning

confidence: 99%

Cardiac involvement in hydrocarbon inhalant toxicity — role of cardiac magnetic resonance imaging: A case report

Jolly¹,

Davis²,

Ali³

et al. 2021

WJC

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BACKGROUND We report a patient who was diagnosed with toxic myopericarditis secondary to hydrocarbon abuse using cardiac magnetic resonance imaging (CMR). CASE SUMMARY A 25-year-old male presented to emergency department with chest pain for 3 d. Patient also reported sniffing hydrocarbon containing inhalant for the last 1 year. Labs showed elevated troponin and electrocardiography was suggestive of acute pericarditis. Echocardiogram showed left ventricular (LV) ejection fraction (EF) of 40%. Given patient’s troponin elevation and reduced EF, cardiac catheterization was performed which showed normal coronaries. CMR was performed for myocardial infarction with non-obstructive coronary arteries evaluation. CMR showed borderline LV function with edema in mid and apical LV suggestive of myocarditis. CONCLUSION CMR can be used to diagnose toxic myopericarditis secondary to hydrocarbon abuse.

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Section: Discussionmentioning

confidence: 99%

Cardiac involvement in hydrocarbon inhalant toxicity — role of cardiac magnetic resonance imaging: A case report

Jolly¹,

Davis²,

Ali³

et al. 2021

WJC

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“…The use of current specific laboratory tests, such as urinary trichloroethanol and chlorinated hydrocarbons, is limited by their high costs, variable turnaround time, and scant availability [ 9 ]. While the presentation of patients may vary, acute inhalant toxicity has generally been associated with central nervous system (CNS) depression, metabolic acidosis, and arrhythmia, as the patient presented in this case [ 10 ]. In addition, inhalants can cause anoxia, respiratory depression, and vagal inhibition, all of which also contribute to CNS depression with variable duration [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Acute Inhalant-Induced Atrial Fibrillation With Severe Hypocalcemia: A Case Report and Review of the Pathophysiology

George¹,

Chin²,

Neeki³

et al. 2021

Cureus

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The recreational use of inhalants is associated with various detrimental health effects ranging from inebriation to cardiac arrest. It also presents a challenging clinical problem as the diagnosis is made by the presentation and patient's history, which is often difficult to obtain in an intoxicated or obtunded individual. The incidence of inhalant use is relatively high. National surveys have reported that nearly 21.7 million Americans aged 12 and older have used inhaled substances at least once in their lives. There is no reversal agent or antidote for inhalants and supportive care is generally recommended. We present a case of a young patient presenting with acute inhalant toxicity accompanied by atrial fibrillation with a rapid ventricular response and severe hypocalcemia.

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“…Subsequent identified effect of long-term alcohol consumption is cardiomyopathy, which is anticipated due to oxidative stress, interference with calcium management, and mitochondrial dysfunction [22,23]. Cocaine use and overdose cause cardiac ischemia, insanity, and fatal arrhythmias that need to be managed quickly to prevent property loss [24,25].…”

Section: Complications Of Illicit Drugs Addictionmentioning

confidence: 99%

Illicit Drugs Addiction among Patients with Chronic Diseases: Simple Review Article

AlRuwaili¹,

Mohammad²,

Alnathir³

et al. 2022

Pharmacophore

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Over the preceding 10 years, fatalities of the groups of individuals who use substances and those who are made homeless in the United Kingdom (UK) have grown massively. The world is now more conscious of how prescription opioid drugs may give a bad impact, like as overdose fatalities and addiction, thanks to the current opioid epidemic in North America. Recent health policies and therapeutic recommendations for the management of chronic noncancer pain are based on a "pharmacovigilance" paradigm, which has expanded specialized care for all chronic pain patients' overdose and dependence management strategies. Thus, physicians agreed on recommendations not to prescribe opioids for chronic noncancer discomfort to people with a history of substance use. These restrictive events have strengthened the boundary between people categorized as "genuine" chronic discomfort patients and those categorized as "drug addicts" who are believed to be more likely to misuse opioid medication. Intoxications frequently cross hand-in-hand with behavior, as they could both be the challenge of dependency or the propelling issue to behavioral disruptions and suicidal tendencies. For that reason, consult with the following listing of intoxications/overdoses and their respective cures.

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Drug Abuse-Induced Cardiac Arrhythmias: Mechanisms and Management

Cited by 3 publications

References 69 publications

Cardiac involvement in hydrocarbon inhalant toxicity — role of cardiac magnetic resonance imaging: A case report

Cardiac involvement in hydrocarbon inhalant toxicity — role of cardiac magnetic resonance imaging: A case report

Acute Inhalant-Induced Atrial Fibrillation With Severe Hypocalcemia: A Case Report and Review of the Pathophysiology

Illicit Drugs Addiction among Patients with Chronic Diseases: Simple Review Article

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