Rural livelihoods in the Andean region evolve in a setting shaped not only by the actions of people, but also by other factors often outside their control, such as climate variation, political and institutional change, and markets. A household economic portfolio approach framed in the context of rural livelihoods allows us to look at the patterns of change in an Andean community through the 1990s, as it adjusts to drought events, changing market conditions, and new institutions. A group of households from a community in the Bolivian Altiplano (high plateau) participated in a panel study that captured information on their activities, resources and life cycle characteristics. Household portfolios of both in-kind and cash income generating activities, which include sheep and cattle production, are constructed. Distinct strategies are found, which are shaped mostly by life cycle characteristics, and by access to resources and assets. Sheep, both criollo (native) and improved, play a key and constant role in the changing livelihood strategies. While other activities grow or shrink in response to market conditions -dairy and potato production -income from sheep does not, as this activity is closely linked to household consumption and welfare expenditures. Though the role of both sheep and cattle increase in prominence during climatic stress periods as an important coping mechanism to smooth consumption, differences exist among the diverse set of rural livelihood strategies identified and their impact on individuals, which require distinct policy interventions to foster security.