Drosophila melanogaster as a Versatile Model for Studying Medically Important Insect Vector-Borne Parasites

Fruit fly for anticancer drug discovery and repurposing

“…To address such issues, comprehensive screening of cancer drug candidates was introduced, aiming to find suitable candidates with effective dose to treat cancer but with less side effects 4 . However, in the in-vivo context, preclinical mammalian models are difficult to be used as a high-throughput screening platform due to economical and ethical issues 5 . To increase the chance to obtain prospective anticancer drug candidates with desired properties, the use of fruit fly Drosophila melanogaster as an in-vivo preclinical model has been introduced.…”