Droplet manipulation in a microfluidic chamber with acoustic radiation pressure and acoustic streaming

Cheung, Yin Nee; Nguyen, Nam‐Trung; Wong, Teck Neng

doi:10.1039/c4sm01453g

Cited by 25 publications

(18 citation statements)

References 49 publications

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“…It is fair to say that droplet technology in microfluidic chambers is well developed and so its scope will not be treated in detail here. These procedures however involve acoustic actuation at low frequencies which are not generally employed in sonochemistry and in which radiation pressure and acoustic streaming play pivotal roles [52]. Likewise, surface acoustic waves (SAWs), which operate at high frequencies (MHz region), and which are generated by applying an oscillating electrical signal to microelectrodes, have been incorporated into microfluidic devices and enable droplet manipulation.…”

Section: Ultrasound Reactors Associated With Flow Micro-meso-fluidic mentioning

confidence: 99%

Enabling technologies built on a sonochemical platform: Challenges and opportunities

Cintas¹,

Tagliapietra

Caporaso

et al. 2015

Ultrasonics Sonochemistry

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Scientific and technological progress now occurs at the interface between two or more scientific and technical disciplines while chemistry is intertwined with almost all scientific domains. Complementary and synergistic effects have been found in the overlay between sonochemistry and other enabling technologies such as mechanochemistry, microwave chemistry and flow-chemistry. Although their nature and effects are intrinsically different, these techniques share the ability to significantly activate most chemical processes and peculiar phenomena. These studies offer a comprehensive overview of sonochemistry, provide a better understanding of correlated phenomena (mechanochemical effects, hot spots, etc.), and pave the way for emerging applications which unite hybrid reactors.

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Section: Ultrasound Reactors Associated With Flow Micro-meso-fluidic mentioning

confidence: 99%

Enabling technologies built on a sonochemical platform: Challenges and opportunities

Cintas¹,

Tagliapietra

Caporaso

et al. 2015

Ultrasonics Sonochemistry

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“…Acoustouidics has been successfully applied to many different research studies, ranging from micro-droplet production and manipulation to micro-particle (or cell) sorting, focusing, separation, mixing and arraying. [16][17][18][19][20][21][22][23][24][25][26][27] Among these possible applications, cell separation has attracted a lot of attention including substantial effort devoted towards enabling the isolation of circulating tumor cells from human blood samples. [28][29][30][31][32][33][34][35][36] Several groups have demonstrated the possibility of isolating target cells from a given sample containing a mix of cells with different characteristics using acoustouidics.…”

Section: Introductionmentioning

confidence: 99%

Separation efficiency maximization in acoustofluidic systems: study of the sample launch-position

2018

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“…Microscale particles manipulation has been widely studied with the help of microfluidic devices . Not surprisingly, such techniques have also been applied to the manipulation of bacteria.…”

Section: Introductionmentioning

confidence: 99%

Effect of dielectrophoretic force on swimming bacteria

Tran

Marcos

2015

Electrophoresis

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Dielectrophoresis (DEP) has been applied widely in bacterial manipulation such as separating, concentrating, and focusing. Previous studies primarily focused on the collective effects of DEP force on the bacterial population. However, the influence of DEP force on the swimming of a single bacterium had not been investigated. In this study, we present a model to analyze the effect of DEP force on a swimming helically flagellated bacterium, particularly on its swimming direction and velocity. We consider a simple DEP force that acts along the X-direction, and its strength as well as direction varies with the X- and Y-positions. Resistive force theory is employed to compute the hydrodynamic force on the bacterium's flagellar bundle, and the effects of both DEP force and rotational diffusion on the swimming of the bacterium are simultaneously taken into consideration using the Fokker-Planck equation. We show the mechanism of how DEP force alters the orientation and velocity of the bacterium. In most cases, the DEP force dominantly influences the orientation of the swimming bacterium; however, when the DEP force strongly varies along the Y-direction, the rotational diffusion is also responsible for determining the bacterium's reorientation. More interestingly, the variance of DEP force along the Y-direction causes the bacterium to experience a translational velocity perpendicular to its primary axis, and this phenomenon could be utilized to focus the bacteria. Finally, we show the feasibility of applying our findings to achieve bacterial focusing.

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Droplet manipulation in a microfluidic chamber with acoustic radiation pressure and acoustic streaming

Cited by 25 publications

References 49 publications

Enabling technologies built on a sonochemical platform: Challenges and opportunities

Enabling technologies built on a sonochemical platform: Challenges and opportunities

Separation efficiency maximization in acoustofluidic systems: study of the sample launch-position

Effect of dielectrophoretic force on swimming bacteria

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