Driving effect of multiplex factors on human brucellosis in high incidence region, implication for brucellosis based on one health concept

Peng, Ruihao; Wang, Ying; Zhai, Jing; Zhang, Jinsong; Lu, Yuying; Yi, Huaimin; Yan, Haozhen; Peng, Yuanli; Sharav, Tumenjargal; Chen, Zeliang

doi:10.1016/j.onehlt.2022.100449

Cited by 9 publications

(13 citation statements)

References 35 publications

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“…Therefore, the ideal controlling and preventing strategy for brucellosis, similar to other zoonoses, is to focus on the complicated interaction between human-animal-environment interfaces. This is essential for public health interventions to alleviate disease risk [ 73 ]. Brucellosis control has become a target of economic development by the WHO and other development agencies due to the huge threat to human health and its high endemic level of animal brucellosis.…”

Section: Discussionmentioning

confidence: 99%

An Epidemiological Study of Brucellosis in Different Animal Species from the Al-Qassim Region, Saudi Arabia

Almuzaini

2023

Vaccines

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Brucellosis is a zoonotic bacterial illness that affects humans and a variety of domestic animals, especially ruminants. It is mostly transmitted through the consumption of contaminated drinks, foods, undercooked meat, or unpasteurized milk or contact with infected animals. Therefore, the present study aimed to investigate the seroprevalence of brucellosis in camels, sheep, and goat herds in the Qassim region, Saudi Arabia, using commonly used diagnostic serological procedures such as the Rose Bengal test (RBT), complement fixation test (CFT), and enzyme-linked immunosorbent assay (ELISA). The seroprevalence of brucellosis in camels, sheep, and goats was determined in the selected areas using a cross-sectional study design and a total of 690 farm animals of both sexes of different ages from the three animal species (274 camels, 227 sheep, and 189 goats). According to RBT results, 65 sera were positive for brucellosis, including 15 (5.47%) for camels, 32 (14.09%) for sheep, and 18 (9.50%) for goats. CFT and c-ELISA were performed as confirmatory tests on positive samples resulting from RBT. With c-ELISA, 60 serum samples were confirmed positive, in 14 (5.10%), 30 (13.21%), and 16 (8.46%) camels, sheep, and goats, respectively. There were 59 serum samples confirmed as positive for CFT, including 14 (5.11%), 29 (12.77%), and 16 (8.46%) for camels, sheep, and goats, respectively. Overall, the highest seroprevalence of brucellosis was found in sheep while the least was found in camels from the three tests (RBT, c-ELISA, and CFT). The highest seroprevalence of brucellosis was found in sheep while the least seroprevalence was found in camels. There was also a higher seroprevalence of brucellosis among female animals than males as well as among old animals than young animals. The study, thus, demonstrates brucellosis seroprevalence among farm animals (camels, sheep, and goats) and the significance of intervention measures against brucellosis incidence in both humans and animals through the creation of public awareness and other relevant policy measures such as livestock vaccination, effective hygiene management, and adequate quarantine or serological analysis for newly introduced animals.

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Section: Discussionmentioning

confidence: 99%

An Epidemiological Study of Brucellosis in Different Animal Species from the Al-Qassim Region, Saudi Arabia

Almuzaini

2023

Vaccines

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“…For threshold‐independent method, we have chosen the area under curve (AUC) value as the best evaluation indicator. We choose the Kappa test and correctly classified instances (CCI) as a threshold‐dependent validation method 28 …”

Section: Methodsmentioning

confidence: 99%

“…We choose the Kappa test and correctly classified instances (CCI) as a threshold-dependent validation method. 28…”

Section: Spatial Distribution Model Analysismentioning

confidence: 99%

Spatial risk of Haemaphysalis longicornis borne Dabieshan tick virus (DBTV) in China

Han,

Gao,

Xin

et al. 2024

Journal of Medical Virology

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The uncertainty and unknowability of emerging infectious diseases have caused many major public health and security incidents in recent years. As a new tick‐borne disease, Dabieshan tick virus (DBTV) necessitate systematic epidemiological and spatial distribution analysis. In this study, tick samples from Liaoning Province were collected and used to evaluate distribution of DBTV in ticks. Outbreak points of DBTV and the records of the vector Haemaphysalis longicornis in China were collected and used to establish a prediction model using niche model combined with environmental factors. We found that H. longicornis and DBTV were widely distributed in Liaoning Province. The risk analysis results showed that the DBTV in the eastern provinces of China has a high risk, and the risk is greatly influenced by elevation, land cover, and meteorological factors. The risk geographical area predicted by the model is significantly larger than the detected positive areas, indicating that the etiological survey is seriously insufficient. This study provided molecular and important epidemiological evidence for etiological ecology of DBTV. The predicted high‐risk areas indicated the insufficient monitoring and risk evaluation and the necessity of future monitoring and control work.

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“…Brucellosis or undulant fever is a zoonotic infectious disease [1,2] epidemic in more than 170 countries and regions with approximately 500,000 new cases annually and which causes economic losses on a billion-dollar scale [3][4][5]. Brucellosis is rarely reported and the pre-1980s situation of serious outbreaks in China [6] had been reduced to a low level of uctuation by government-led monitoring and prevention during the early 1990s [7,8].…”

Section: Introductionmentioning

confidence: 99%

Changing trends in human brucellosis in pastoral and agricultural China, 2004–2019: A Joinpoint regression analysis

Ma,

Liu,

Zhao

et al. 2023

Preprint

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Background Brucellosis, a zoonotic disease caused by Brucella species, poses a significant public health concern in China, particularly in pastoral and areas. The incidence of human brucellosis has risen sharply in China but little is known about trends in pastoral and agricultural areas respectively. Methods Annual and monthly incidence and numbers of reported cases of human brucellosis in regional China between 2004 and 2019 were accessed from the National Public Health Science Data Sharing Center, and the annual percentage change (APC) in pastoral and agricultural areas was calculated. Annual and monthly trends were analyzed by the Joinpoint regression model. Results 569016 cases of human brucellosis were reported between 2004 and 2019 with a peak in 2014. A trend of increasing incidence was found (AAPC = 6.3%, 95% CI: 3.2–9.4%) with higher rates in pastoral areas but greater mean increases in agricultural (AAPC = 9.4) and agricultural/pastoral areas (AAPC = 7.7) than in pastoral areas (AAPC = 5.9). Infections occurred throughout the year with a concentration of cases between March and July. Increasing monthly incidence was found in all types of areas from January to May (APC > 0) and a decreasing monthly trend was seen from May to December (APC < 0, p < 0.05). Conclusions The incidence of human brucellosis was higher in pastoral areas of China than in agricultural/pastoral or agricultural areas, however, the rate of increase was higher in agricultural/pastoral and agricultural areas than in pastoral areas. Epidemic surveillance should be strengthened in key counties (cities, districts) and prevention and control measures increased nationwide.

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Driving effect of multiplex factors on human brucellosis in high incidence region, implication for brucellosis based on one health concept

Cited by 9 publications

References 35 publications

An Epidemiological Study of Brucellosis in Different Animal Species from the Al-Qassim Region, Saudi Arabia

An Epidemiological Study of Brucellosis in Different Animal Species from the Al-Qassim Region, Saudi Arabia

Spatial risk of Haemaphysalis longicornis borne Dabieshan tick virus (DBTV) in China

Changing trends in human brucellosis in pastoral and agricultural China, 2004–2019: A Joinpoint regression analysis

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