Drinking water source and human Toxoplasma gondii infection in the United States: a cross-sectional analysis of NHANES data

Krueger, Whitney S.; Hilborn, Elizabeth D.; Converse, Reagan R.; Wade, Timothy J.

doi:10.1186/1471-2458-14-711

Cited by 43 publications

(30 citation statements)

References 34 publications

(52 reference statements)

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“…In this study, we found that keeping cats at home was highly associated with T. gondii seropositivity (aOR 5·060, 95% CI 2·814-9·100, P < 0·001). Some previous reports have indicated that humans can become infected with T. gondii through ingesting tissue cysts in undercooked or raw meat from an infected intermediate host, or by ingestion of oocytes via unwashed vegetables and fruit or drinking water polluted by the faeces of an infected cat [4,[20][21][22]. Similarly, our study found that consumption of raw/undercooked meat was highly associated with T. gondii seropositivity (aOR 2·438, 95% CI 1·167-5·096, P = 0·018).…”

Section: Discussionsupporting

confidence: 66%

Seroprevalence and associated risk factors ofToxoplasma gondiiinfection in psychiatric patients: a case-control study in eastern China

et al. 2015

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In recent years, the effect of Toxoplasma gondii infection on the cerebrum and neuropsychiatric patients has been increasingly highlighted. However, there is limited information about the epidemiology of T. gondii infection in psychiatric patients in Shandong province, eastern China. Therefore, through a case-control study, 445 patients hospitalized for diacrisis or treatment in Weihai, eastern China, and 445 control subjects from the general population of the same region matched by gender, age, and residence were examined with enzyme-linked immunoassays for the presence of IgG and IgM antibodies to T. gondii and associated sociodemographic and behavioural characteristics in a population of psychiatric patients. Seroprevalence of IgG antibodies to T. gondii in psychiatric patients (77/445, 17·30%) was significantly higher than in control subjects (55/445, 12·36%) (P = 0·038). Fourteen (3·15%) psychiatric patients and 10 (2·25%) control subjects had IgM antibodies to T. gondii (P = 0·408). Multivariate analysis using logic regression showed that T. gondii infection was associated with cats at home and consumption of raw/undercooked meat in psychiatric patients. Considering that most psychiatric patients usually have lower cognitive functioning and additional transmission routes related to their inappropriate behaviours that could enhance the risk of infection, psychiatric patients should be considered as a specific group of T. gondii infection.

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Section: Discussionsupporting

confidence: 66%

Seroprevalence and associated risk factors ofToxoplasma gondiiinfection in psychiatric patients: a case-control study in eastern China

et al. 2015

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“…Humans become infected postnatally, mainly by ingesting tissue cysts from undercooked meat or from food or drink contaminated with oocysts shed in cat feces [22, 34]. Ingestion of poorly cooked meat from sheep, and possibly consumption of non-pasteurized contaminated milk from sheep are considered important sources of transmission of T. gondii to humans [4, 7, 18, 21, 27].…”

Section: Introductionmentioning

confidence: 99%

Seroprevalence ofToxoplasma gondiiinfection and risk factors in domestic sheep in Henan province, central China

Zhang¹,

Wang²,

Wang³

et al. 2016

Parasite

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Sheep are highly susceptible to infections with Toxoplasma gondii and play a major role in the transmission of toxoplasmosis to humans. In the present study, 779 serum samples from sheep were collected from Henan province, central China from March 2015 to May 2016, and antibodies to T. gondii were detected by modified agglutination test (MAT). The overall seroprevalence of T. gondii in sheep was 12.71% (99/779). The risk factors significantly associated with T. gondii seroprevalence were the geographical origin, age, presence of cats, and the rearing system. This is the first report of T. gondii infection in sheep in Henan province, central China, and of an association of seropositivity to T. gondii with risk factors.

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“…The diagnosis of toxoplasmosis is most commonly made by detecting the immunoglobulin (IgG and IgG avidity) antibodies in the serum samples of patients using variety methods (ELISA, IFA, IgM-ISAGA, etc). [21][22][23][24][25] Sometimes, congenital toxoplasmosis received from undercooked meat. In spite of the fact that antibody to Toxoplasma is widely prevalent in human throughout the world, clinical toxoplasmosis is less common.…”

Section: Discussionmentioning

confidence: 99%

Electrochemiluminesence Epidemiologic Detection of Toxoplasma gondii Infection in Pregnant Women With Direct and Indirect Diagnostic Techniques (ELISA Avidity Plus Biochemical Assay)

Bahadory

Ghaffari

Namrood

et al. 2018

Int J Epidemiol Res

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Background and aims:Toxoplasmosis is a very common disease in the world. Two types of acquired toxoplasmosis have been detected. In the chronic toxoplasmosis, the abnormality of tissue function is little but, in acute toxoplasmosis, function of RES system becomes interrupted. The assessment of toxoplasma antibody with tissue enzymes in this stage is very important. Furthermore, serum ferritin in some conditions became high in acute phase of infectious disease. Methods: This study was based on comparative abundance study. Materials consisted of 980 serum and amniotic fluid samples collected from human blood with high level of IgG antibody against Toxoplasma gondii in Rajaie center, Tehran, Iran. The standard test was ELISA assay to detect these antibodies and the main test was measurement of liver transaminases (SGOT, SGPT) bilirubin and ferritin to evaluate acute toxoplasmosis. Data analysis was done by SPSS version 18.0. This study was done during March to June, 2017. Results: Results showed that in some patients with high level of IgG AVIDITY antibody against T. gondii the level of liver transaminases, serum bilirubin and ferritin became increased. For example in 120 patients with acute toxoplasmosis the mean serum levels of SGOT were 108 IU/L and in 80 patients the mean serum bilirubin were about 5 mg/dL. Conclusion: In acute congenital toxoplasmosis, the evaluation of IgG AVIDITY was first step and then the measurement of biochemical factors such as serum transaminases, serum Bilirubin and serum Ferritin were important.

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Drinking water source and human Toxoplasma gondii infection in the United States: a cross-sectional analysis of NHANES data

Cited by 43 publications

References 34 publications

Seroprevalence and associated risk factors ofToxoplasma gondiiinfection in psychiatric patients: a case-control study in eastern China

Seroprevalence and associated risk factors ofToxoplasma gondiiinfection in psychiatric patients: a case-control study in eastern China

Seroprevalence ofToxoplasma gondiiinfection and risk factors in domestic sheep in Henan province, central China

Electrochemiluminesence Epidemiologic Detection of Toxoplasma gondii Infection in Pregnant Women With Direct and Indirect Diagnostic Techniques (ELISA Avidity Plus Biochemical Assay)

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