Dried plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway

In recent times, plums have been described as foods with health-promoting properties. Research on the health effects of plum continue to show promising results on its antiinflammatory, antioxidant and memory-improving characteristics. The increased interest in plum research has been attributed to its high phenolic content, mostly the anthocyanins, which are known to be natural antioxidants. A systematic review of literature was carried out to summarize the available evidence on the impact of plums (Prunus species; domestica and salicina) on disease risk factors and health outcomes. A number of databases were searched according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for relevant studies on plum health effects in vitro, animal studies and clinical trials. A total of 73 relevant peer-reviewed journal articles were included in this review. The level of evidence remains low. Of the 25 human studies, 6 were confirmatory studies of moderate quality, while 19 were exploratory. Plums have been shown to possess antioxidant and antiallergic properties, and consumption is associated with improved cognitive function, bone health parameters and cardiovascular risk factors. Most of the human trials used the dried version of plums rather than fresh fruit, thus limiting translation to dietary messages of the positioning of plums in a healthy diet. Evidence on the health effect of plums has not been extensively studied, and the available evidence needs further confirmation. Copyright © 2016 John Wiley & Sons, Ltd.

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“…Bone quality improvement (restoring bone density) with all doses (Franklin et al, 2006) USA Dried plum (P.…”

Section: Domestica)mentioning

confidence: 99%

A Systematic Review on the Health Effects of Plums (Prunus domestica and Prunus salicina)

Igwe

Charlton

2016

Phytotherapy Research

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“…Previous studies have reported that under stressful situations, such as during an ovariectomy, inflammation (Puel et al, 2006), and obesity (Shen et al, 2012), polyphenols from olive oil and green tea improved bone strength and reduced bone loss in mice and rats. Polyphenol-containing plants, such as dried plum (Franklin et al, 2006), blueberry (Devareddy et al, 2008), green, black, red, and white tea (Shen et al, 2012;Tomaszewska et al, 2016), have demonstrated positive effects on bone health in different rat models (ovariectomy, inflammation, obesity, cadmium and lead exposure, etc.). A substantial amount of research on olive polyphenols has shown positive effects on bone health.…”

Section: Pinteraction Walnut Oilmentioning

confidence: 99%

Effects of Olive Leaf and Marigold Extracts on the Utilization of Nutrients and on Bone Mineralization using Two Different Oil Sources in Broilers

et al. 2018

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The aim of this study was to investigate the effects of olive leaf and marigold extracts on the apparent total tract digestibility (ATTD) of the principal nutrients and energy, as well as on mineral utilization (Ca, P, Mg, Mn, Fe, Cu and Zn) in relation to bone characteristics in broilers fed walnut-or linseed oil-supplemented diets. Thirty-six 12-dayold commercial broilers Ross 308 were reared in metabolic cages, assigned to one of the six dietary treatments (3×2 factorial design): three supplements (not supplemented, olive leaf extract, or marigold extract), and two oils (walnut or linseed oil). The results showed that the marigold extract reduced Zn and P balances and tended to lower the balance of ash and Mg, and the ATTD of Zn and Mg. Diets with linseed oil increased the ATTD of acid detergent fiber and reduced the ATTD of the organic residue and Cu. No differences in the bone characteristics of tibia were observed between treatments. These results indicated that the inclusion of marigold extract had a negative effect on the Zn and P balance, and that neither extract had any major effect on the digestion and utilization of energy and other investigated nutrients, or on bone mineralization, irrespective of the oil source included in the diet.

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“…Kajian terdahulu menunjukkan terdapat beberapa percanggahan dalam keputusan kajian mengenai kesan polifenol terhadap osteokalsin. Pemberian plum kering kepada tikus terovariektomi tidak menunjukkan sebarang perubahan yang signifikan pada kedua-dua ekspresi gen serta aras serum osteokalsin (Franklin et al 2006;Rendina et al 2013). Akan tetapi, kajian menggunakan beri biru pula meningkatkan kedua-duanya .…”

Section: Diet Dan Rawatanunclassified

Tindakan Minyak Kelapa Dara terhadap Tulang Osteoporosis Pascamenopaus: Analisis Gen Osteoblastogenesis dan Antioksidan

Abdul-Hamid

Muhammad²,

Mohamed³

2016

JSM

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Dried plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway

Cited by 108 publications

References 53 publications

A Systematic Review on the Health Effects of Plums (Prunus domestica and Prunus salicina)

A Systematic Review on the Health Effects of Plums (Prunus domestica and Prunus salicina)

Effects of Olive Leaf and Marigold Extracts on the Utilization of Nutrients and on Bone Mineralization using Two Different Oil Sources in Broilers

Tindakan Minyak Kelapa Dara terhadap Tulang Osteoporosis Pascamenopaus: Analisis Gen Osteoblastogenesis dan Antioksidan

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