Drew-Anderson technique attenuates systemic inflammatory response syndrome and improves respiratory function after coronary artery bypass grafting

Richter, J; Meisner, H; Tassani, Peter; Barankay, A; Dietrich, Wulf; Braun, S

doi:10.1016/s0003-4975(99)01131-5

Cited by 84 publications

(51 citation statements)

References 20 publications

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“…The authors found that in this cohort of patients managed with low levels of PEEP (4 [2. [2][3][4][5], median ), the utilization of low tidal volumes (below 8 ml/kg of predicted body weight) were associated with increased mortality. This suggests that low PEEP levels should not be associated with low tidal volumes….…”

Section: Positive End-expiratory Pressurementioning

confidence: 97%

“…Several mechanisms are potentially involved and include ischemia-reperfusion phenomena, ventilation disorders or overload-related lung injury due to transfusion or early respiratory mechanics impairment (1)(2)(3)(4). Systemic inflammation due to ECC and aggressive high tidal volume ventilation can cause non-cardiogenic pulmonary edema or other organ failure (5)(6)(7).…”

Section: Introductionmentioning

confidence: 99%

“…To be effectively contained, ischemia-reperfusion lesions necessitate no disruption in pulmonary artery blood flow, which can be achieved with specific ECC methods but further complicates the proceeding (3,4). Conversely, adequate ventilatory strategies could prevent from various lung injuries to appear, such as atelectasis, which lead to intra-pulmonary shunt and are the leading cause of postoperative hypoxemia (5).…”

Section: Introductionmentioning

confidence: 99%

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Perioperative ventilatory strategies in cardiac surgery

Lellouche

Delorme

Bussières

et al. 2015

Best Practice & Research Clinical Anaesthesiology

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Section: Positive End-expiratory Pressurementioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Perioperative ventilatory strategies in cardiac surgery

Lellouche

Delorme

Bussières

et al. 2015

Best Practice & Research Clinical Anaesthesiology

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“…They noted that all pathological changes of acute lung injury that occured during CPB were avoided in the study group. In CABG operations Richter et al (14) developed a system (Drew-Anderson technique), in which the patients used their own lungs as the oxygenator. By this, they reported that pulmonary and other organ damages caused by systemic infl ammation during CPB were seen least.…”

Section: Discussionmentioning

confidence: 99%

Does preoperative administration of allopurinol protect the lungs from ischemia–reperfusion injury occuring during cardiopulmonary bypass?

Görmüş¹,

Çelik²,

Ergene³

et al. 2013

BLL

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Abstract:Background: It is investigated whether preoperative allopurinol administration protects lung injury induced by cardiopulmonary bypass (CPB). Methods: Sixty patients with coronary artery disease who need elective coronary artery bypass grafting operations by using CPB were taken into this study. They were divided into two groups; control and allopurinol. Allopurinol (300 mg/day) was administered to the latter group during the preoperative period of 5 days. Standard CPB procedures were used in all cases. Blood was sampled for TNF-alpha, IL-6, IL-8, IL-10 before anesthesia (T0), after anesthesia and before skin incision (T1), before CPB (T2), after aortic declamping (T3), at the end of CPB (T4), 6 hours after operation (T5), 12 hours after operation (T6), and 24 hours after operation (T7). Pulmonary function test (PFT) was performed before and following the 6th day of operation. Results: TNF-alpha, IL-6, IL-8 increased in both groups at T3, T4, T5 and T6 compared to control (p<0.05). TNF-alpha, IL-6, and IL-8 levels were lower in group A at T3, T4, T5 and T6 (p<0.05). Creatinin phosphokinase (CK) levels were lower in group A at T6 (p<0.05). CK-MB levels were lower in group A than in group C (p<0.05). Pulmonary function test (PFT) did not yield any differences between the groups. Conclusions: Preoperative allopurinol administration decreases the infl ammation and myocardial injury according to biochemical markers of ischemia reperfusion injury. However, this biochemical success does not rebound to PFT (Tab. 5, Ref. 15). Full Text in PDF www.elis.sk.

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“…Postoperative pulmonary dysfunction may be the result of multiple insults from various aspects of CPB surgery, including extra-CPB factors (general anesthesia, sternotomy, postoperative pain with hypoventilation, breach of the pleura, surgical woundrelated inflammatory response) and intra-CPB factors (blood contact with artificial material, loss of arterial physiologic pulsation, lung ischemia/ reperfusion, pulmonary air and/or fat embolism, hypothermia, lung ventilator arrest) (3)(4)(5)(6)(7). Overall, blood contact with artificial material, lung ischemia/ reperfusion injury, and CPB-induced nonphysiologic linear perfusions are considered the main causes of dysfunction (7).…”

mentioning

confidence: 99%

A Meta‐Analysis of Pulmonary Function With Pulsatile Perfusion in Cardiac Surgery

et al. 2014

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The aim of this study was to determine whether pulsatile or nonpulsatile perfusion had a greater effect on pulmonary dysfunction in randomized controlled trials. MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were used to identify available articles published before April 13, 2013. A meta-analysis was conducted on the effects of pulsatile perfusion on postoperative pulmonary function, intubation time, and the lengths of intensive care unit (ICU) and hospital stays. Eight studies involving 474 patients who received pulsatile perfusion and 496 patients who received nonpulsatile perfusion during cardiopulmonary bypass (CPB) were considered in the meta-analysis. Patients receiving pulsatile perfusion had a significantly greater PaO2 /FiO2 ratio 24 h and 48 h post-operation (P < 0.00001, both) and significantly lower chest radiograph scores at 24 h and 48 h post-operation (P < 0.00001 and P = 0.001, respectively) compared with patients receiving nonpulsatile perfusion. The incidence of noninvasive ventilation for acute respiratory insufficiency was significantly lower (P < 0.00001), and intubation time and ICU and hospital stays were shorter (P = 0.004, P < 0.00001, and P < 0.00001, respectively) in patients receiving pulsatile perfusion during CPB compared with patients receiving nonpulsatile perfusion. In conclusion, our meta-analysis suggests that the use of pulsatile flow during CPB results in better postoperative pulmonary function and shorter ICU and hospital stays.

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Drew-Anderson technique attenuates systemic inflammatory response syndrome and improves respiratory function after coronary artery bypass grafting

Cited by 84 publications

References 20 publications

Perioperative ventilatory strategies in cardiac surgery

Perioperative ventilatory strategies in cardiac surgery

Does preoperative administration of allopurinol protect the lungs from ischemia–reperfusion injury occuring during cardiopulmonary bypass?

A Meta‐Analysis of Pulmonary Function With Pulsatile Perfusion in Cardiac Surgery

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