Drépanocytose homozygote chez l'adulte ivoirien de plus de 21 ans

Influence of the Clinical Status on Stress Reticulocytes, CD 36 and CD 49d of SSFA2Homozygous Sickle Cell Patients Followed in Abidjan

“…Data on age and sex were similar to the other studies carried out in Abidjan which stressed that sickle cell patients were mostly teenagers or young male adults [ 10 , 11 ].…”

“…Maintenance treatment is based on folic acid and vasodilators [ 10 ]. Crises are treated by nonsteroidal anti-inflammatory drugs, particularly ketoprofen [ 10 , 11 ].…”

Morbidity and mortality of sickle cell disease patients is unaffected by splenectomy: evidence from three decades of follow-up in a high-income setting

“…Pairwise comparisons of proportions with Bonferroni correction show that the percentage of patients that underwent splenectomy was greater in patients with the Sß 0 genotype (53%) than in the Sß + group (34%, p=0.0012) and in the SS group (9.6%, p<0.001) (Sß 0 > Sß + > SS) (Table 1). In our cohort, the rate of splenectomy in SS patients was close to that reported in other studies with similar SS population (Figure S2) [8][9][10][11][12][13][14] . Noteworthy, the rate of splenectomy in our Sß patients was higher than that described by Belhani et al and Diagne et al, who carried out their studies on smallest Sß patient population in African countries 9,12,14 .…”

Profil socio-démographique et économique des adultes drépanocytaires régulièrement suivis au Centre Hospitalier Universitaire de Libreville

“…L´absence d´exploitation de 145 dossiers, en l´absence de registre, permet de penser que ce nombre est sous-estimé. Notre étude a montré que la drépanocytose adulte affecte la tranche d´âge comprise entre 25 et 29 ans, supérieure à celle observée en Côte d´Ivoire et au Sénégal [ 7 , 8 ]. L´existence dans ces pays d´unités de prise en charge de l´adulte drépanocytaire permettant une transition organisée de la consultation pédiatrique à celle de l´adulte drépanocytaire, pourrait être un argument expliquant cet écart.…”