Dreidimensionale Dicken- und Volumenbestimmung des Kniegelenkknorpels in der MRT: Validierung am anatomischen Präparat mittels CT-Arthrographie

Abstract

The results suggest that, based on a fat-suppressed FLASH sequence with high resolution and three-dimensional concepts of digital image analysis, the cartilage volume and thickness can be analysed non-invasively and with high accuracy by MRI.

Determination of 3D cartilage thickness data from MR imaging: Computational method and reproducibility in the living

“…It has been shown that MRI is capable of providing accurate data on cartilage volume (8)(9)(10)(11)(12) and thickness (11)(12)(13)(14), if high-resolution T1-weighted, fat-suppressed, three-dimensional (3D) gradient-echo sequences are employed. Since in geometrically complex joint surfaces the appropriate distance vectors are not always located within the MR image plane, 3D techniques are required that take into account the spatial orientation of the thickness measurements within the cartilage layer (11,(15)(16)(17)(18)(19). Such techniques make it possible to determine the cartilage thickness distribution throughout entire joint surfaces, independent of the respective section location and orientation, and this is of particular importance for obtaining a satisfactory reproducibility in longitudinal studies, in which identical section locations and orientation cannot be readily reproduced (20,21).…”

“…Such techniques make it possible to determine the cartilage thickness distribution throughout entire joint surfaces, independent of the respective section location and orientation, and this is of particular importance for obtaining a satisfactory reproducibility in longitudinal studies, in which identical section locations and orientation cannot be readily reproduced (20,21). In previous studies 3D cartilage thickness measurements (based on 3D reconstruction of MR images) have been presented (11,(16)(17)(18)(19)(20)(21), by demonstrating thickness maps throughout human knee joint surfaces. However, some of these techniques (11,(16)(17)(18) have suffered from limitations:…”

“…In previous studies 3D cartilage thickness measurements (based on 3D reconstruction of MR images) have been presented (11,(16)(17)(18)(19)(20)(21), by demonstrating thickness maps throughout human knee joint surfaces. However, some of these techniques (11,(16)(17)(18) have suffered from limitations:…”

Diagnostische Wertigkeit der MR-tomographischen Knorpelläsionsdarstellung im Vergleich mit der intraoperativen Arthroskopie bei Calcaneusfrakturen

“…Die MRT des Calcaneus wurde zunächst zur Frakturevaluation be- [21]. Auch dreidimensionale volumetrische Quantifizierungen [22] und eine automatisierte Erfassung der Knorpeldicke sind möglich [23], in jedem Fall jedoch eine sensitive, reproduzierbare und quantitative Knorpelläsionsdiagnostik [12,13]. Wir verwendeten ein einheitliches MRT-Protokoll, welches dem Vorschlag von Uhl entspricht [24].…”

“…Eine standardisierte Sequenzwahl wurde bisher nicht erreicht, jedoch werden fast ausschließlich fettsaturierte Sequenzen wegen der reduzierten Chemical-Shift-Artefakte und hyalinen Knorpelalterationen empfohlen, wobei T1-gewichtete 3D-Gradientenechosequenzen ein hervorragendes Signal-Rausch-Verhältnis und eine gute räumliche Auflösung bieten [12,13,15].…”