Dramatic response to intravitreal Bevacizumab in hypertensive retinopathy

Abstract

Hypertensive retinopathy is seen frequently in patients with systemic hypertension and is usually asymptomatic. An acute rise in blood pressure may lead to exudative changes in the form of macular edema, hemorrhages, and serous macular detachment that can lead to visual decline. The authors report prompt resolution of exudative changes in a case of hypertensive retinopathy following intravitreal bevacizumab.

Comment on: Dramatic response to intravitreal bevacizumab in hypertensive retinopathy

“…I read with great interest the article “Dramatic response to intravitreal bevacizumab in hypertensive retinopathy” by Padhy and Kumar. [1] The authors have attributed rapid resolution of intra-retinal and sub-retinal fluid at macula in both eyes following intravitreal injection of bevacizumab only in the right eye. Systemic absorption of intravitreal bevacizumab had been cited as a reason for improvement in fellow eye.…”

Comment on: Dramatic response to intravitreal bevacizumab in hypertensive retinopathy

“…We read with interest the case report[1] on the resolution of bilateral subfoveal fluid and disc edema due to hypertensive retinopathy (HTNR) after unilateral intravitreal bevacizumab. We want to discuss few points.…”

“…Salman[3] used intravitreal bevacizumab in 12 cases of persistent HTNR despite control of hypertension for 1 month and noted stabilization and improvement of vision in all cases. This paper[1] also adds to the evidence[45] that anti-VEGF agents may be helpful in HTNR. The exact role of anti-VEGF agents in HTNR needs further exploration, but these agents may add to the armamentarium to treat the cases of HTNR with subfoveal fluid which do not resolve despite good systemic control.…”

Response to comment on: Dramatic response to intravitreal Bevacizumab in hypertensive retinopathy

“…We would like to thank the authors for their interest and comments on the article “Dramatic response to intravitreal Bevacizumab in Hypertensive Retinopathy”[12] and address their queries as follows:…”