Dramatic case of paediatric pyoderma gangrenosum

Chen, Jingsi; Wang, Hua; Ren, Faliang

doi:10.1136/archdischild-2020-320598

Cited by 2 publications

(4 citation statements)

References 4 publications

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“…"Prompt diagnosis and treatment are essential to avoid severe scarring that can affect aesthetic and mental health. Notably, systemic comorbidities, such as inflammatory bowel disease, occurred in approximately 50% of PG cases in children" [13]. Regardless of the absence of symptoms of systemic comorbidities in our patient, further long-term multidisciplinary follow-up is necessary.…”

Section: Fig 2 Skin Biopsy Of the Erythematous Margins Of The Ulcer S...mentioning

confidence: 77%

“…This girl presented with recurrent multiple painful ulcerative lesions for 10 months. The ulcer on the forehead rapidly progressed and involved both cheeks and nose" [13]. "Another article reported the case of a 3year-old girl who developed PG on the left upper eyelid without prior trauma or associated pathologies" [14].…”

Section: Fig 2 Skin Biopsy Of the Erythematous Margins Of The Ulcer S...mentioning

confidence: 99%

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Pyoderma Gangrenosum at Uncommon Site in a Pediatric Patient: Case Report and Review of Literature

Mehsas

Sektaoui²,

Boubnane³

et al. 2023

AJPR

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A 12-year-old girl presented with three ulcerated lesions on her face that were red, swollen, had advancing borders, and undermined. Despite treatment with intravenous and topical antibiotics, the ulcers did not improve, and cultures showed no growth of organisms. The patient did not have any underlying systemic disease, and a skin biopsy revealed neutrophilic dermatitis. Oral prednisone was started, which resulted in the healing of the lesions. The skin biopsy and positive response to corticosteroids confirmed the diagnosis of Pyoderma Gangrenosum (PG). PG is a rare inflammatory skin condition, and facial lesions are a rare presentation. Early initiation of immunosuppressive therapy is crucial for complete healing and to minimize the significant psychological impact.

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Section: Fig 2 Skin Biopsy Of the Erythematous Margins Of The Ulcer S...mentioning

confidence: 77%

Section: Fig 2 Skin Biopsy Of the Erythematous Margins Of The Ulcer S...mentioning

confidence: 99%

Pyoderma Gangrenosum at Uncommon Site in a Pediatric Patient: Case Report and Review of Literature

Mehsas

Sektaoui²,

Boubnane³

et al. 2023

AJPR

View full text Add to dashboard Cite

show abstract

“…Timely diagnosis and treatment are crucial to avoid unsightly scarring and potential psychological distress. 7 …”

Section: Discussionmentioning

confidence: 99%

“…Timely diagnosis and treatment are crucial to avoid unsightly scarring and potential psychological distress. 7 Notably, standardized diagnostic criteria for PG are currently lacking. PG is an exclusive diagnosis and should be differentiated from ischaemic ulcers, infections, vascular disease, other neutrophilic skin diseases and malignancies.…”

Section: Discussionmentioning

confidence: 99%

A Case of Pustular Pyoderma Gangrenosum Misdiagnosed as Acute Febrile Neutrophilic Dermatosis in a Pediatric Patient

Yang,

Wu,

Jiang

et al. 2024

CCID

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Background Pyoderma gangrenosum (PG) is a rare cause of skin ulcers in children, posing challenges in diagnosis and treatment. As the disease is often associated with conditions such as inflammatory bowel disease (IBD), rheumatoid arthritis, haematological disorders and other diseases, diagnosis and treatment often require cooperation with other medical departments. Accordingly, dissemination of information about the disease to doctors in departments other than dermatologists, especially paediatricians, can help in its early detection. Case Presentation The 11-year-old pediatric patient in the case initially diagnosed with acute febrile neutrophilic dermatosis was eventually confirmed as pustular PG through histopathological examinations of skin and other relevant examinations. The medical condition is lessened after treatment with a combination of glucocorticoids and adalimumab. Conclusion PG is relatively rare in clinical settings, particularly among pediatric patients exhibiting persistent high fever and signs of pustular pyoderma gangrenosum. This case underscores the importance of considering the potential diagnosis of pediatric pustular PG when confronted with a child presenting persistent high fever and pustules after trauma. Additionally, the proactive initiation of adalimumab emerges as a promising treatment option for pediatric IBD -associated pustular PG.

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Dramatic case of paediatric pyoderma gangrenosum

Cited by 2 publications

References 4 publications

Pyoderma Gangrenosum at Uncommon Site in a Pediatric Patient: Case Report and Review of Literature

Pyoderma Gangrenosum at Uncommon Site in a Pediatric Patient: Case Report and Review of Literature

A Case of Pustular Pyoderma Gangrenosum Misdiagnosed as Acute Febrile Neutrophilic Dermatosis in a Pediatric Patient

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