Drainage, Streptomycin and Tuberculosis

Brock, Benjamin L.

doi:10.1378/chest.16.2.129

Diseases of the Chest

1949

DOI: 10.1378/chest.16.2.129

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Drainage, Streptomycin and Tuberculosis

Benjamin L. Brock

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1951

1970

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“…Streptomycin is an aminoglycoside antibiotic with a wide range of effects on Escherichia coli (2). One result of the cell-streptomycin interaction is loss of viability, which has been attributed to an interaction with the ribosomes (9).…”

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confidence: 99%

Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T ⁻

Carlson

Bockrath

1970

J Bacteriol

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Escherichia coli strain WWU was found to be moderately resistant to streptomycin when grown in a minimal medium, although the strain was sensitive if grown in nutrient broth. Transfer experiments showed that cells grown in minimal medium retain the resistant state for a period of time after dilution into nutrient broth; and conversely, sensitive cells grown in nutrient broth were sensitive after dilution into minimal medium for a period of time. The kinetics of transition from resistant to sensitive and from sensitive to resistant were observed, and kinetics of 3 H-dihydrostreptomycin accumulation by resistant and sensitive cells were compared. The data suggested that cells grown in minimal medium were physiologically resistant because they accumulated streptomycin poorly. Inactivation per incorporated antibiotic molecule was the same in resistant and sensitive cells.

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Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T ⁻

Carlson

Bockrath

1970

J Bacteriol

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Streptomycin and Artificial Pneumoperitoneum in the Treatment of Pulmonary Tuberculosis

Brock

1951

Diseases of the Chest

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Drainage, Streptomycin and Tuberculosis

Cited by 2 publications

References 11 publications

Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T ⁻

Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T ⁻

Streptomycin and Artificial Pneumoperitoneum in the Treatment of Pulmonary Tuberculosis

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Drainage, Streptomycin and Tuberculosis

Cited by 2 publications

References 11 publications

Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T −

Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T −

Streptomycin and Artificial Pneumoperitoneum in the Treatment of Pulmonary Tuberculosis

Contact Info

Product

Resources

About

Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T ⁻

Physiological Streptomycin Resistance in a Multiauxotroph of Escherichia coli Strain 15 T ⁻