Draft Genome Sequence of the Green Microalga
            <i>Chlorella</i>
            sp. Strain BAC9706, Isolated from Lake Baikal, Russia

Petrushin, Ivan S.; Беликов, С. И.; Белых, О. И.; Тихонова, И. В.; Chernogor, Lubov

doi:10.1128/mra.00966-20

Cited by 1 publication

(1 citation statement)

References 9 publications

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“…In the past decade, since the publication of the Chlorella variabilis draft whole genome (Blanc et al ., 2010), the first to be published from the genus Chlorella , 16 other Chlorella genomes have been published. These genomes have helped researchers to gain new insights into the evolution of the genus, adaptation to environmental cues, lipid biosynthesis and other metabolic processes (Blanc et al ., 2010; Juneja et al ., 2016; Zuñiga et al ., 2016; Arriola et al ., 2018; Guarnieri et al ., 2018; Cecchin et al ., 2019; Petrushin Ivan et al ., 2020).…”

Section: Introductionmentioning

confidence: 99%

Genomic imprints of unparalleled growth

Murik,

Geffen,

Shotland

et al. 2023

New Phytologist

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Summary Chlorella ohadii was isolated from desert biological soil crusts, one of the harshest habitats on Earth, and is emerging as an exciting new green model for studying growth, photosynthesis and metabolism under a wide range of conditions. Here, we compared the genome of C. ohadii, the fastest growing alga on record, to that of other green algae, to reveal the genomic imprints empowering its unparalleled growth rate and resistance to various stressors, including extreme illumination. This included the genome of its close relative, but slower growing and photodamage sensitive, C. sorokiniana UTEX 1663. A larger number of ribosome‐encoding genes, high intron abundance, increased codon bias and unique genes potentially involved in metabolic flexibility and resistance to photodamage are all consistent with the faster growth of C. ohadii. Some of these characteristics highlight general trends in Chlorophyta and Chlorella spp. evolution, and others open new broad avenues for mechanistic exploration of their relationship with growth. This work entails a unique case study for the genomic adaptations and costs of exceptionally fast growth and sheds light on the genomic signatures of fast growth in photosynthetic cells. It also provides an important resource for future studies leveraging the unique properties of C. ohadii for photosynthesis and stress response research alongside their utilization for synthetic biology and biotechnology aims.

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