Draft Genome Sequence of Extended-Spectrum Beta-Lactamase-Producing Serratia fonticola BWK15 Isolated from Feces of
            <i>Anas penelope</i>

Kenzaka, Takehiko; Tani, Katsuji

doi:10.1128/genomea.01102-17

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…fonticola of animal origin. Based on the nucleotide sequence similarity analysis between bla SFDC‐1 and the other genes retrieved from the database, we found that the 10 genes [including nine from the NCBI nucleotide database with similarities of >91.72% and one reported in a recent publication with a similarity of 97.91% (Kenzaka and Tani, 2017)] were all from S . fonticola except for those of undetermined origin, with all the other genes showing a similarity of less than 74.0%.…”

Section: Discussionmentioning

confidence: 99%

Characterization and identification of SFDC‐1, a novel AmpC‐type β‐lactamase in Serratia fonticola

Zhang

Zhou

et al. 2021

Environmental Microbiology

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The clinical and environmental infections caused by AmpC β-lactamases have been increasingly reported recently. In this study, we characterize the novel chromosome-encoded AmpC β-lactamase SFDC-1 identified in Serratia fonticola strain R28, which was isolated from a rabbit raised on a farm in southern China. SFDC-1 shared the highest amino acid identity of 79.6% with the functionally characterized AmpC β-lactamase gene bla YRC-1 , although it had highly homologous functionally uncharacterized relatives in the same species from different sources, including some of the clinical significance. The cloned bla SFDC-1 exhibited resistance to a broad spectrum of β-lactam antibiotics, including most cephalosporins with the highest resistance to ampicillin, cefazolin and ceftazidime, with increased MIC levels ≥128-fold compared with the control strains. The purified SFDC-1 showed catalytic activities against β-lactams with the highest catalytic activity to cefazolin. The genetic context of bla SFDC-1 and its relatives was conserved in the chromosome, and no mobile genetic elements were found surrounding them.

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Section: Discussionmentioning

confidence: 99%

Characterization and identification of SFDC‐1, a novel AmpC‐type β‐lactamase in Serratia fonticola

Zhang

Zhou

et al. 2021

Environmental Microbiology

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“…Interestingly, all of S. fonticola isolates were from surface water, indicating the environmental origin of S. fonticola and that they are widely disseminated in the aquatic ecosystem. Previous studies also suggest an environmental origin for S. fonticola, as β-lactamase-positive S. fonticola have been frequently isolated from vegetables, birds, soil, and surface water [29][30][31][32] and a carbapenem-resistant S. fonticola was isolated from drinking water [33]. Although S. fonticola is not typically pathogenic, the presence of ESBL-producing and carbapenem-resistant S. fonticola in the environment could be a public health concern as they could be vectors for the AR dissemination in the environment and to humans.…”

Section: Esbl-producing Enterobacteriaceae and Crementioning

confidence: 97%

Distribution of Antibiotic Resistance in a Mixed-Use Watershed and the Impact of Wastewater Treatment Plants on Antibiotic Resistance in Surface Water

Cho,

Hiott,

Read

et al. 2023

Antibiotics

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The aquatic environment has been recognized as a source of antibiotic resistance (AR) that factors into the One Health approach to combat AR. To provide much needed data on AR in the environment, a comprehensive survey of antibiotic-resistant bacteria (ARB), antibiotic resistance genes (ARGs), and antibiotic residues was conducted in a mixed-use watershed and wastewater treatment plants (WWTPs) within the watershed to evaluate these contaminants in surface water. A culture-based approach was used to determine prevalence and diversity of ARB in surface water. Low levels of AR Salmonella (9.6%) and Escherichia coli (6.5%) were detected, while all Enterococcus were resistant to at least one tested antibiotic. Fewer than 20% of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (17.3%) and carbapenem-resistant Enterobacteriaceae (CRE) (7.7%) were recovered. Six ARGs were detected using qPCR, primarily the erythromycin-resistance gene, ermB. Of the 26 antibiotics measured, almost all water samples (98.7%) had detectable levels of antibiotics. Analysis of wastewater samples from three WWTPs showed that WWTPs did not completely remove AR contaminants. ARGs and antibiotics were detected in all the WWTP effluent discharges, indicating that WWTPs are the source of AR contaminants in receiving water. However, no significant difference in ARGs and antibiotics between the upstream and downstream water suggests that there are other sources of AR contamination. The widespread occurrence and abundance of medically important antibiotics, bacteria resistant to antibiotics used for human and veterinary purposes, and the genes associated with resistance to these antibiotics, may potentially pose risks to the local populations exposed to these water sources.

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Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States

et al. 2022

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Draft Genome Sequence of Extended-Spectrum Beta-Lactamase-Producing Serratia fonticola BWK15 Isolated from Feces of Anas penelope

Cited by 5 publications

References 8 publications

Characterization and identification of SFDC‐1, a novel AmpC‐type β‐lactamase in Serratia fonticola

Characterization and identification of SFDC‐1, a novel AmpC‐type β‐lactamase in Serratia fonticola

Distribution of Antibiotic Resistance in a Mixed-Use Watershed and the Impact of Wastewater Treatment Plants on Antibiotic Resistance in Surface Water

Isolation of AmpC- and extended spectrum β-lactamase-producing Enterobacterales from fresh vegetables in the United States

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