Draft clinical guidelines of the Russian Society of Paediatric Gastroenterologists, Hepatologists and Nutritionists on diagnosis and treatment of functional gastrointestinal disorders in children

Belmer, S.V.; Волынец, Г. В.; Гурова, М. М.; Zvyagin, A.A.; Корниенко, Е. А.; Новикова, В. П.; Pechkurov, D.V.; Privorotskiy, Valeriy Feliksovich; Tyazheva, A.A.; Fayzullina, R.A.; Хавкин, А.И.; Erdes, S.I.

doi:10.20953/1727-5784-2019-6-27-48

Cited by 7 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Эта дисахаридаза расщепляет содержащиеся в изобилии в бобовых, овощах и злаках углеводы раффинозу, стахиозу и вербаскозу до усвояемых -галактозы и сахарозы, предотвращая, таким образом, метеоризм. В этом же контексте, пациентам с СРК-Д, СРК-См, а также ПИ-СРК показано назначение препаратов на основе бета-галактозидазы (лактазы), что обосновано при ускоренном транзите нутриентов по кишке с последующим гидролизом лактозы толстокишечной микробиотой и, как результат, повышенным газообразованием [5,[10][11][12][13].…”

Section: дифференциальный диагнозunclassified

“…Это связано с тем, что, наряду с другими причинами, обусловливающими дебют CРК, нарушение количественно-качественных характеристик микробиоты и, соответственно, оси «микробиотакишка-мозг», как одого из основополагающих эпигенетических факторов [10,14,16]. При постинфекционном СРК различного генеза (вирусного, бактериального, связанного с простейшими, или глистной инвазией) целесообразно проведение кишечной деконтаминации.…”

Section: Lactobacillius Acidophilus Bifi Dobacterium Bb-12unclassified

“…Особенности СРК в детском возрасте, такие как многообразие этиологческих факторов и вариантов болевого синдрома, большее влияние вегетативного статуса на характер и время возникновения болей, большая распространенность постинфекционных форм СРК (ПИ-СРК) у детей, а также ограничение диагностических возможностей и противопоказания к назначению ряда лекарственных препаратов в детском возрасте [10][11][12][13], приводят к необходимости разработке клинических рекомендаций СРК с позиций детского возраста. Эти особенности были учтены, при создании рекомендаций Российского общества детских гастроэнтерологов, гепатологов и нутрициологов.…”

unclassified

See 2 more Smart Citations

Irritable bowel syndrome in children: evolution of manifestations

Belmer

Гурова

Zvyagin

et al. 2023

jour

View full text Add to dashboard Cite

The article provides an analysis of changes in ideas about pathogenetic mechanisms, approaches to the diagnosis and treatment of irritable bowel syndrome in children. Current data on the pathophysiological mechanisms of IBS are presented. Algorithms for the management of children with this pathology are presented, based on the new positions of the Rome IV criteria and Russian recommendations for the diagnosis and treatment of functional disorders of the digestive system in children.

show abstract

Section: дифференциальный диагнозunclassified

Section: Lactobacillius Acidophilus Bifi Dobacterium Bb-12unclassified

unclassified

See 1 more Smart Citation

Irritable bowel syndrome in children: evolution of manifestations

Belmer

Гурова

Zvyagin

et al. 2023

jour

View full text Add to dashboard Cite

show abstract

“…Функциональные нарушения занимают одно из ведущих мест в структуре патологии органов пищеварения у детей различных возрастных групп, представляя собой медицинскую и социальную проблему [1][2][3][4]. Важнейшим звеном патогенеза функциональных расстройств органов пищеварения (ФРОП), наряду с феноменом висцеральной гиперчувствительности и генетической предрасположенности, являются нарушения микробиоценоза кишечника [5][6][7][8].…”

Section: Introductionunclassified

Personalized symbiontic therapy for children with functional digestive disorders

Гончар

Alekhina

Tsapieva

et al. 2022

jour

View full text Add to dashboard Cite

The aim of the study was to identify the features of the influence of autoprobiotic and probiotic E. faecium strains on clinical and laboratory parameters in children with functional gastroenterological pathology.Patients and methods. In the period 2020–2021. 35 children over 3 years of age with functional gastrointestinal disorders (FGID) were observed on an outpatient basis, who were prescribed an autoprobiotic or probiotic strain E. faecium for therapeutic purposes and recommended a diet.The study protocol provided for clinical and anamnestic screening, FGID diagnostics; analysis of coprograms and assessment of the composition of the intestinal microbiota in children before and after a course of probiotics. The study of intestinal microbiota was carried out by RT-PCR in feces using a set of primers “Colonoflor”. One patient was excluded from the study due to refusal to take the autoprobiotic.The rest of the patients formed two groups: group 1 (n = 16)—children who received the autoprobiotic strain and group 2 (n = 18)—children who received the conditionally “reference” strain E. faecium L3. Probiotics were used in the form of a liquid form (which is a starter culture based on soy protein isolates containing 109 CFU in 1 ml) at a dose of 25 ml 2 times a day for 10 days.The results of using probiotic strains were evaluated on the basis of data from a survey of parents about the state of children and the dynamics of clinical manifestations, as well as changes in the values of indicators of coprograms and the composition of the intestinal microbiota.Statistical processing of the results was carried out using Student’s t-test, Mann-Whitney U-test; Wilcoxon test. The results were considered reliable at a significance level of p <0.05.Results. Studies of the effect of prescribing E. faecium L3 strain and an autoprobiotic strain to children with FROP revealed a positive effect on the clinical symptoms of the disease (in 29.4% and 25%, respectively) in the absence of undesirable side effects. Analysis of the dynamics of coprograms revealed an equivalent positive dynamics in the form of improvement in most of the studied stool characteristics. The study of the composition of the intestinal microbiota in the observed children revealed a low level of Lactobacilli and Enterococcus before and after the administration of probiotics. After the course of the E. faecium L3 strain, a significant increase in the content of F. prausnitzii was noted. The use of an autoprobiotic strain contributed to a significant decrease in the frequency of isolation of conditionally pathogenic bacteria in large numbersConclusion. The course appointment of autoprobiotic and probiotic E. faecium strains in children with FGID has a positive effect on clinical symptoms, improvement of most coprogram indices and normalization of the intestinal microbiota composition.

show abstract

Laparoscopic dissection in children with celiac artery compression syndrome

Zainulabidov

Razumovsky

Mitupov

et al. 2021

Russian Journal of Pediatric Surgery, Anesthesia and Intensive

View full text Add to dashboard Cite

BACKGROUND: A cause of abdominal pain in children may be compression stenosis of the celiac trunk (Dunbars syndrome). This disease occurs when the median arcuate ligament of the diaphragm compresses the celiac trunk, thereby creating compression stenosis, causing the arterial hemodynamics in the artery to suffer and provide adequate blood circulation to the abdominal cavity organs. Medical statistics indicate that 10% to 15% of children and adolescents suffering from chronic abdominal pain have compression stenosis of the celiac trunk. AIM: This study aims to improve the diagnostic results and identify the indications for the surgical treatment of children with compression stenosis of the celiac trunk. MATERIALS AND METHODS: From 2015 to 2020 at the N.F. Filatov Childrens Hospital, 64 patients, aged 4 to 17 years underwent surgical treatment for compression stenosis of the celiac trunk. There are 42 boys (66%) and 22 girls (34%). The leading clinical manifestation in all patients was abdominal pain. Associated surgical pathology was observed in 34 of them. The diagnosis was based on anamnesis, examination, ultrasound examination with Doppler and celiac trunk blood flow measurements, multispiral computed tomography, and angiography. RESULTS: After completing the examination, 61 patients underwent laparoscopic decompression of the celiac trunk, and three children were operated on using the laparotomic approach. In all cases, the leading cause of compression stenosis of the celiac trunk was the median arcuate ligament of the diaphragm combined with the neurofibrous tissue of the celiac plexus. The average duration of the operation was 50 minutes. Intraoperative blood loss did not exceed 530 ml. One conversion completed. There were no postoperative complications in the early postoperative period. The patients were discharged in satisfactory condition. The control examination was conducted in the period from six months to three years. In 97% of patients, clinical symptoms of abdominal ischemia were not detected. CONCLUSION: Our experience indicates the possibility of diagnosing compression stenosis of the celiac trunk in children at early disease stages and laparoscopic treatment success of patients with this disease.

show abstract

Draft clinical guidelines of the Russian Society of Paediatric Gastroenterologists, Hepatologists and Nutritionists on diagnosis and treatment of functional gastrointestinal disorders in children

Cited by 7 publications

References 0 publications

Irritable bowel syndrome in children: evolution of manifestations

Irritable bowel syndrome in children: evolution of manifestations

Personalized symbiontic therapy for children with functional digestive disorders

Laparoscopic dissection in children with celiac artery compression syndrome

Contact Info

Product

Resources

About