Cell Reports volume 4, issue 1, P10-18 2013 DOI: 10.1016/j.celrep.2013.05.040 View full text
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Hongjie Li, Yanyan Qi, Heinrich Jasper

Abstract: Summary The gastrointestinal tract is lined by a series of epithelia that share functional requirements, but also have distinct, highly specialized roles. Distinct populations of somatic stem cells (SCs) regenerate these epithelia, yet the mechanisms that maintain regional identities of these SCs are not well understood. Here, we identify a role for the BMP-like Dpp signaling pathway in diversifying regenerative processes in the adult gastrointestinal tract of Drosophila. Dpp secreted from enterocytes at the …

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