This chapter discusses the importance of Information Technology to spatial location and city competitiveness. Understanding spatial location in urban networks can be informed by economic geography concepts, especially those with insights into how urban areas form and develop. Relative distance to markets and the flow of goods and services influences the spatial position of cities, shapes how urban settlements evolve, and helps explain their distribution. Concepts like accessibility and centrality—and strategies for measuring them—can be used to determine a good place to locate a business or transportation hub. This chapter makes a case for the importance of considering information utilities, especially telecommunication networks, as important part of economic geography, and ultimately the growth and competitiveness of cities.