Downregulation of the Expression of Steroidogenic Acute Regulatory
Protein and Aromatase in Steroidogenic KGN Human Granulosa Cells after Exposure
to Bisphenol A
Ji-Eun Park,
Seung Gee Lee,
Seung-Jin Lee
et al.
Abstract:Although increasing evidence of cause-and-effect relationship between BPA
exposure and female reproductive disorders have been suggested through many
studies, the precise biochemical and molecular mechanism(s) by which BPA
interferes with steroidogenesis in the ovarian cells still remain unclear.
Therefore, the purpose of this study was to discover the steroidogenic
biomarker(s) associated with BPA treatment in human granulosa cell line, KGN. In
this study, our results obtained via the analysis of steroidogene… Show more
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