Abstract:Background: Substantial evidence has demonstrated that impact exercise can help adolescents to accumulate more bone mass. However, the effect of OB (osteoblast) on promoting bone formation during impact exercise remains to be explored. This study aimed to examine the mechanism for downhill running promoting bone formation ability and bone mineralization ability by activating the TGF-β (transforming growth factor-β)/Smad pathway in growing mice.
Methods: Four-week-old C57BL/6 female mice (n = 28) were randomly… Show more
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