Down syndrome and pulmonary hemosiderosis: an under-recognized association

Alimi, Aurélia; Taytard, Jessica; Taam, Rola Abou; Houdouin, Véronique; Forgeron, Aude; Lavadera, Marc Lubrano; Cros, Pierrick; Gibertini, I.; Derelle, J.; Deschildre, A.; Thumerelle, C.; Epaud, Ralph; Reix, Philippe; Fayon, Michaël; Roullaud, Sylvie; Troussier, Françoise; Renoux, Monique; Blic, J. de; Leyronnas, Sophie; Thouvenin, Guillaume; Périsson, Caroline; Ravel, Aimé; Clément, Annick; Corvol, Harriet; Nathan, Nadia

doi:10.1183/13993003.congress-2018.pa2237

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“…In addition to the classical rare DPLDs, there were several reports on ultrarare diseases affecting adults and children. A limi et al [87] reported that nine out of 34 patients with pulmonary haemosiderosis had Down syndrome, and this group had more severe disease with increased dyspnoea (p=0.03) and pulmonary arterial hypertension (p=0.01). Additionally, all the three reported deaths occurred in the Down syndrome group.…”

Section: Introductionmentioning

confidence: 99%

Research highlights from the 2018 ERS International Congress: interstitial lung diseases

et al. 2019

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This article reviews a selection of the scientific presentations on interstitial lung disease (ILD)/diffuse parenchymal lung disease (DPLD) that were made at the 2018 European Respiratory Society (ERS) International Congress in Paris. A number of advances in the epidemiology, pathogenesis, diagnosis and treatment of these disorders were presented and discussed by clinicians and researchers. The research topics span over all four groups of ERS Assembly 12: Interstitial Lung Diseases (Group 12.01: Idiopathic interstitial pneumonias; Group 12.02: ILD/DPLD of known origin; Group 12.03: Sarcoidosis and other granulomatous ILD/DPLD; Group 12.04: Rare ILD/DPLD).

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Section: Introductionmentioning

confidence: 99%