“…Phenotypes listed in Table 1 as oxidative stress-related consist largely of sensitivity to an oxidizing agent such as peroxide, in the case of ypc1 Δ (Higgins et al, 2002), sur2 Δ (Berry et al, 2011), csg1 Δ (Berry et al, 2011), isc1 Δ (Almeida et al, 2008; Berry et al, 2011; Chang et al, 2002), and elo2 Δ (Berry et al, 2011), or MMS as in ypc1 Δ (Begley et al, 2002), scs7 Δ (Begley et al, 2002), and isc1 Δ (Chang et al, 2002; Matmati et al, 2009). There are also cases of resistance phenotypes such as the fas1 Δ strain (deleted in the fatty acid synthetase gene FAS1) resistance to hydrogen peroxide (Matias et al, 2007), and the reported increased genomic stability of lac1 Δ when challenged with the non-proteogenic amino acid canavanine (Alabrudzinska et al, 2011). The elo1 Δ and elo2 Δ strains also show ROS accumulation and oxidative stress sensitivity, when transformed with the human α-synuclein protein as part of a Parkinson’s disease model (Lee et al, 2011).…”