Down-regulation of ESRP2 inhibits breast cancer cell proliferation via inhibiting cyclinD1
Caiping He,
Yuting Chen,
Ximin Zhang
et al.
Abstract:Background
Epithelial splicing regulatory protein 2 (ESRP2),an important alternative splicing protein of mRNA, is reported to have a dual role in tumors, which can promote or inhibit the occurrence and development of tumors. However, the function and mechanism of ESRP2 in breast cancer (BC) remain unclear.
Methods
The distribution of ESRP2 expression in breast cancer and the correlation between ESRP2 expression and the overall survival rate were detected by The Cancer Genome Atlas (TCGA) database. Gene Ontol… Show more
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