Douleur chronique cancéreuse et analgésie intrathécale : expérience de trois centres de lutte contre le cancer

Refractory Cancer Pain and Intrathecal Therapy: Critical Review of a Systematic Review

“…Two studies were secondary analyses of a randomized controlled study and were excluded [10,11]. One paper was not retrieved from the search engines used [12]. One was a registry study designed to conduct ongoing nonrandomized, active prospective postmarket surveillance of neuromodulation products [13].…”

Prise en charge des douleurs cancéreuses rebelles : stratégies pratiques

“…Du fait de la mise en place de procédures spécifiques, notamment en termes d'asepsie (gestes techniques d'implantation et remplissage de la pompe), les complications sont restées moins fré-quentes que dans la littérature internationale. Cette étude démontre l'intérêt (en termes d'efficacité et de sécurité) de recourir à une pharmacothérapie antalgique intrathécale délivrée par pompe implantée chez des patients cancéreux sélectionnés » [44].…”

In Vitro Stability of Low-Concentration Ziconotide Alone or in Admixtures in Intrathecal Pumps

“…In addition, these admixtures have been the focus of consensus conferences, particularly in the United States, aimed at defining drug incrementation protocols . Intrathecal analgesia was introduced more recently in France, particularly for patients with cancer .…”

“…In this study, we evaluated the following points: ziconotide stability at different concentrations, in admixture with morphine sulfate, ropivacaine, and clonidine, in mean concentrations used in clinical practice ziconotide stability alone at low concentrations used in clinical practice, in intrathecal pumps, to assess the influence of other drugs on the stability of ziconotide ziconotide stability alone at low concentrations or with other drugs in syringes kept at 5°C to determine the optimal time from admixture preparation to delivery and to validate storage conditions …”