Double uteri with cervicovaginal agenesis

Singh, Gurcharan; Sunita, Venigalla

doi:10.1016/j.fertnstert.2008.06.048

Cited by 5 publications

(5 citation statements)

References 4 publications

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“…This approach was adopted by Acien et al in their revised 'Clinical and embryological classification of the malformations of the female genital tract' (Table 2), which could lead to a better understanding of complex malformations before deciding on the best therapeutic approach [34]. The same approach was adopted by Oppelt et al with the VCUAM classification (Table 3) [55], which describes anomalies by relating them to their anatomical origin, making it possible to identify complex anomalies in a precise fashion that makes it easier to provide suitable clinical care for affected patients [76]. These classifications are yet to be widely accepted among clinicians.…”

Section: Classification Of Congenital Uterine Anomaliesmentioning

confidence: 99%

“…The same approach was adopted by Oppelt et al . with the VCUAM classification (Table 3) [55], which describes anomalies by relating them to their anatomical origin, making it possible to identify complex anomalies in a precise fashion that makes it easier to provide suitable clinical care for affected patients [76]. These classifications are yet to be widely accepted among clinicians.…”

Section: Normal and Abnormal Uterine Developmentmentioning

confidence: 99%

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Congenital Uterine Anomalies and their Impact on Fertility

Hassan

Lavery

Trew

2010

Womens Health (Lond Engl)

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Congenital uterine anomalies are not uncommon. Many are asymptomatic and have been associated with normal and adverse reproductive outcomes. The interference of these anomalies with a patient's fertility is an interesting but still debatable issue, and the proper management of infertile women with many forms of these anomalies remains controversial. The current literature regarding the frequency and probable causes of infertility among women with congenital uterine anomalies is insufficient to allow any robust conclusions to be drawn. Diagnostic and selection bias, a lack of objective diagnostic criteria for the different anomaly types and heterogeneity of study designs have contributed to the conflicting results from different studies of the prevalence of these anomalies among the infertile and fertile populations. However, emerging evidence from recent literature suggests causal associations between these anomalies (particularly the septate uterus) and infertility, and demonstrates significant improvements in the fecundity of women with septate uteri and otherwise unexplained infertility after hysteroscopic metroplasty. This review provides a critical update of the state of knowledge regarding congenital uterine anomalies, our current understanding of their effect on fertility and discusses how they can be managed from the reproductive perspective.

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Section: Classification Of Congenital Uterine Anomaliesmentioning

confidence: 99%

Section: Normal and Abnormal Uterine Developmentmentioning

confidence: 99%

Congenital Uterine Anomalies and their Impact on Fertility

Hassan

Lavery

Trew

2010

Womens Health (Lond Engl)

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“…The V agina, C ervix, U terus, A dnex – associated M alformation (VCUAM) classification (Table 1 ) was introduced in 2005 to allow an accurate description of genital and associated malformations [ 8 - 11 ].…”

Section: Introductionmentioning

confidence: 99%

Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH)

Oppelt

Lermann

Strick

et al. 2012

Reprod Biol Endocrinol

120

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BackgroundThe aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM).Methods290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy.ResultsClassification of female genital malformation according to the Vagina Cervix Uterus Adnex – associated Malformation classification system was possible in 284 women (97.9%). Complete atresia of Vagina (V5b) and bilateral atresia of Cervix (C2b) were found in 284 patients (100%). Uterus: bilateral rudimentary or a plastic uterine horns were found in 239 women (84.2%). Adnexa: normal Adnexa were found in 248 women (87.3%). Malformations: associated malformations were found in 126 of 282 evaluable women (44.7%), 84 women (29.6%) had malformations of the renal system. Of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome 212 women (74.7%) could be classified as V5bC2bU4bA0. The most frequent classification was V5bC2bU4bA0M0 (46.8%) diagnosed in 133 of 284 women.ConclusionsComplete atresia of vagina and cervix were found in all patients, variable malformations were found with uterus and adnexa. A variety of associated malformations were present, predominantly of the renal system. It is therefore recommended that all patients with genital malformations should be evaluated for renal abnormalities.

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“…In the cases presented here, however, there was no advantage of time, because the patients presented with progressive clinical symptoms, so operation had to be instantly planned. The combination of a duplicate functioning uterus with a complete vaginal agenesis constitutes a genuine rarity (10,11). Various reconstructive methods have been described to restore cervicovaginal continuity, o save the patients from mandatory hysterectomy, like standardly recommended in the past (12).…”

Section: Figurementioning

confidence: 99%