Double rare-earth nanothermometer in aqueous media: opening the third optical transparency window to temperature sensing

Skripka, Artiom; Benayas, Antonio; Marin, Riccardo; Canton, Patrizia; Hemmer, Eva; Vetrone, Fiorenzo

doi:10.1039/c6nr08472a

Cited by 152 publications

(103 citation statements)

References 66 publications

(1 reference statement)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In this study, the temperature sensing properties of the naked core and core-shell structure were derived under the condition that the nanoparticles were immersed in cyclohexane liquid. Here we should point out that the most recent investigation proves that the temperature sensing properties of rare earth doped nanoparticles depend also on the immersion liquid environment 72 , thus the obtained results can be different when they are used in in-vivo systems.…”

Section: Resultsmentioning

confidence: 99%

Dually functioned core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles as nano-calorifiers and nano-thermometers for advanced photothermal therapy

Zhang

Chen

et al. 2017

Sci Rep

View full text Add to dashboard Cite

To realize photothermal therapy (PTT) of cancer/tumor both the photothermal conversion and temperature detection are required. Usually, the temperature detection in PTT needs complicated instruments, and the therapy process is out of temperature control in the present investigations. In this work, we attempt to develop a novel material for achieving both the photothermal conversion and temperature sensing and control at the same time. To this end, a core-shell structure with NaYF4:Er3+/Yb3+ core for temperature detection and NaYF4:Tm3+/Yb3+ shell for photothermal conversion was designed and prepared. The crystal structure and morphology of the samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Furthermore, the temperature sensing properties for the NaYF4:Er3+/Yb3+ and core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles were studied. It was found that the temperature sensing performance of the core-shell nanoparticles did not become worse due to coating of NaYF4:Tm3+/Yb3+ shell. The photothermal conversion behaviors were examined in cyclohexane solution based on the temperature response, the NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ core-shell nanoparticles exhibited more effective photothermal conversion than that of NaYF4:Er3+/Yb3+ nanoparticles, and a net temperature increment of about 7 °C was achieved by using the core-shell nanoparticles.

show abstract

Section: Resultsmentioning

confidence: 99%

Dually functioned core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles as nano-calorifiers and nano-thermometers for advanced photothermal therapy

Zhang

Chen

et al. 2017

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Near infrared (NIR) light (700–1800 nm) is translucent to biological tissues due to substantially reduced light scattering and absorption, thus entailing accurate luminescence readout in deep tissues. This spectral range is known to be classified into three “optical biological windows”: the first window (NIR‐I: 700–900 nm), the second window (NIR‐II: 1000–1350 nm), and the third window (NIR‐III: 1500–1870 nm) . The tissue‐penetrating ability promises the use of NIR LIR thermometers for biological uses.…”

Section: Introductionmentioning

confidence: 99%

NIR‐II/III Luminescence Ratiometric Nanothermometry with Phonon‐Tuned Sensitivity

Jia

et al. 2020

Advanced Optical Materials

View full text Add to dashboard Cite

Luminescence nanothermometers are promising for noninvasive, high resolution thermographics ranging from aeronautics to biomedicine. Yet, limited success has been met in the NIR‐II/III biological windows, which allow temperature evaluation in deep tissues. Herein, a new type of phonon‐based ratiometric thermometry is described that utilizes the luminescence intensity ratio (LIR) between holmium (Ho3+) emission at ≈1190 nm (NIR‐II) and erbium (Er3+) emission at ≈1550 nm (NIR‐III) from a set of oxide nanoparticles of varying host lattices. It is shown that multi‐phonon relaxation in Er3+ ions and phonon‐assisted transfer process in Ho3+ ions play a significant role in LIR determination through channeling the harvested excitation energy to the corresponding emitting states. As a result, temperature sensitivity can be tuned by the dominant phonon energy of host lattice, thus endowing aqueous yttrium oxide (Y2O3, 376 cm−1) nanoparticles to have a relative temperature sensitivity of 1.01% K−1 and absolute temperature sensitivity of 0.0127 K−1 at 65 °C in a physiological temperature range (25–65 °C). And their temperature sensing for biological tissues is further explored and the influence of water and chicken breast on thermometry is discussed. This work constitutes a solid step forward to build sensitive NIR‐II/III nanothermometers for biological applications.

show abstract

“…As philosophical as it might sound, this sentence well embodies the spirit of the latest research in the field of optical biomedical techniques. With the advancement of our knowledge around the interaction between light and biological tissues, we quickly realized the advantage of moving further down the electromagnetic spectrum and choosing near‐infrared (NIR) light over visible . The concept of optical transparency windows is now well consolidated and has spurred the development of approaches that make use of specific NIR light to penetrate and probe deeper, with more precision within human tissues.…”

Section: Introductionmentioning

confidence: 99%

Plasmonic Copper Sulfide Nanoparticles Enable Dark Contrast in Optical Coherence Tomography

Marin

Lifante

Besteiro

et al. 2020

Adv Healthcare Materials

View full text Add to dashboard Cite

Optical coherence tomography (OCT) is an imaging technique affording noninvasive optical biopsies. Like for other imaging techniques, the use of dedicated contrast agents helps better discerning biological features of interest during the clinical practice. Although bright OCT contrast agents have been developed, no dark counterpart has been proposed yet. Herein, plasmonic copper sulfide nanoparticles as the first OCT dark contrast agents working in the second optical transparency window are reported. These nanoparticles virtually possess no light scattering capabilities at the OCT working wavelength (≈1300 nm); thus, they exclusively absorb the probing light, which in turn results in dark contrast. The small size of the nanoparticles and the absence of apparent cytotoxicity support the amenability of this system to biomedical applications. Importantly, in the pursuit of systems apt to yield OCT dark contrast, a library of copper sulfide nanoparticles featuring plasmonic resonances spanning the three optical transparency windows is prepared, thus highlighting the versatility and potential of these systems in light‐controlled biomedical applications.

show abstract

Double rare-earth nanothermometer in aqueous media: opening the third optical transparency window to temperature sensing

Cited by 152 publications

References 66 publications

Dually functioned core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles as nano-calorifiers and nano-thermometers for advanced photothermal therapy

Dually functioned core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles as nano-calorifiers and nano-thermometers for advanced photothermal therapy

NIR‐II/III Luminescence Ratiometric Nanothermometry with Phonon‐Tuned Sensitivity

Plasmonic Copper Sulfide Nanoparticles Enable Dark Contrast in Optical Coherence Tomography

Contact Info

Product

Resources

About