Double network hydrogels from polyzwitterions: high mechanical strength and excellent anti-biofouling properties

Yin, Haiyan; Akasaki, Taigo; Sun, Tao Lin; Nakajima, Tasuku; Kurokawa, Takayuki; Nonoyama, Takayuki; Taira, Toshio; Saruwatari, Yoshiyuki; Gong, Jian Ping

doi:10.1039/c3tb20324g

Cited by 106 publications

(91 citation statements)

References 46 publications

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“…11 Furthermore, the q and E of the PCDME hydrogel hardly change with pH until below pH 3. 11 This suggests that, the carboxyl groups of this carboxybetaine type zwitterion are in fully ionic form above pH 3.…”

Section: ■ Introductionmentioning

confidence: 99%

Sliding Friction of Zwitterionic Hydrogel and Its Electrostatic Origin

et al. 2014

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Polyzwitterionic materials, which have both cationic and anionic groups in each repeating unit of polymer, show excellent antibiofouling properties. In this study, the surface friction of carboxybetaine type zwitterionic hydrogels, poly(N-(carboxymethyl)-N,N-dimethyl-2-(methacryloyloxy)-ethanaminium, inner salt) (PCDME), against glass substrates were investigated in aqueous solutions. The friction measurement was performed using a rheometer with parallel plate geometry and the sliding interface was monitored during the measurement. The frictional stress on glass was high in water and it showed weak dependence on pressure as long as the two sliding surfaces were in complete contact. The results performed in solutions with varied ionic strength revealed that the high friction on glass substrates has an electrostatic origin. The electrostatic potential measurement revealed that the PCDME gels have an isoelectric point at pH 8.5. Since the glass substrates carrying negative charges in pure water, the gel and the glass have electrostatic attraction in water. Study on the effect of pH has shown that below pH 8.5, attraction between the positively charged gels and negatively charged glass gives high friction, while above pH 8.5, the electrical double layer repulsion between two negatively charged surfaces gives low friction. From these results, it is concluded that although the PCDME gels behave like neutral gels in the bulk properties, their surface properties sensitively change with pH and ionic strength of the medium. ■ INTRODUCTIONPolyzwitterionic materials, which have both cationic and anionic groups in each repeating unit of polymer, are drawing great attention as biomaterials due to their excellent antibiofouling properties and biocompatibility. 1−10 The antibiofouling materials that prevent the attachment of bioorganisms in wet environment are in a great demand for advanced technologies. Recently a tough double network (DN) hydrogel has been developed by using poly(2-acrylamido-2-methylpropanesulfonic acid) (PAMPS) as the first network and a carboxybetaine type zwitterion poly(N-(carboxymethyl)-N,Ndimethyl-2-(methacryloyloxy)ethanaminium, inner salt) (PCDME) as the second network. 11 Comparing to the conventional double network (DN) hydrogels that use neutral polyacrylamide or poly(dimethyl acrylamide) as the second network, 12 the DN hydrogel using the zwitterionic polymer as the second network exhibits excellent antibiofouling properties in addition to high mechanical strength and toughness. 11 This promises a great potential of the zwitterion-based hydrogels as better candidate for bioapplication, for example, as coating materials of low-friction biomedical devices and implants. Understanding the surface frictional properties of the zwitterion hydrogels is indispensable for these potential applications.As the water-swollen hydrogels have many common features to that of internal organs in our body, the sliding friction of hydrogels in aqueous solution has recently been drawing great scientific attention. 13−24...

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Section: ■ Introductionmentioning

confidence: 99%

Sliding Friction of Zwitterionic Hydrogel and Its Electrostatic Origin

et al. 2014

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“…After the immediate third cycle (ε ¼ 70%), the polyampholyte hydrogel still recovers its original shape and size almost completely after unloading the stress, even though the hysteresis phenomena appears. The good mechanical property of the polyampholyte hydrogel should owe to the fact that the randomness of charges forms multiple ionic bonds with a wide distribution of strengths, through interchain and intrachain complexation (Sun et al, 2013a;Xu et al, 2015;Yin et al, 2013). Moreover, the GO sheets act as chemical crosslinking points in the polyampholyte hydrogel through amination reaction between the epoxy groups of GO and the amino groups in TETA (see the FTIR results shown below).…”

Section: Characterization Of Polyampholyte Hydrogelmentioning

confidence: 99%

A highly efficient polyampholyte hydrogel sorbent based fixed-bed process for heavy metal removal in actual industrial effluent

et al. 2016

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a b s t r a c tHigh sorption capacity, high sorption rate, and fast separation and regeneration for qualified sorbents used in removing heavy metals from wastewater are urgently needed. In this study, a polyampholyte hydrogel was well designed and prepared via a simple radical polymerization procedure. Due to the remarkable mechanical strength, the three-dimensional polyampholyte hydrogel could be fast separated, easily regenerated and highly reused. The sorption capacities were as high as 216.1 mg/g for Pb(II) and 153.8 mg/g for Cd(II) owing to the existence of the large number of active groups. The adsorption could be conducted in a wide pH range of 3e6 and the equilibrium fast reached in 30 min due to its excellent water penetration for highly accessible to metal ions. The fixed-bed column sorption results indicated that the polyampholyte hydrogel was particularly effective in removing Pb(II) and Cd(II) from actual industrial effluent to meet the regulatory requirements. The treatment volumes of actual smelting effluent using one fixed bed column were as high as 684 bed volumes (BV) (7736 mL) for Pb(II) and 200 BV (2262 mL) for Cd(II). Furthermore, the treatment volumes of actual smelting effluent using tandem three columns reached 924 BV (31,351 mL) for Pb(II) and 250 BV (8483 mL) for Cd(II), producing only 4 BV (136 mL) eluent. Compared with the traditional high density slurry (HDS) process with large amount of sludge, the proposed process would be expected to produce only a small amount of sludge. When the treatment volume was controlled below 209.3 BV (7103 mL), all metal ions in the actual industrial effluent could be effectively removed (<0.01 mg/L). This wok develops a highly practical process based on polyampholyte hydrogel sorbents for the removal of heavy metal ions from practical wastewater.

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“…5b, pure PDMS film possessed a tensile Young's modulus, ultimate tensile strength and elongation at break of 1 MPa, 1.8 MPa and 150%, respectively. By comparison, the blue-phase PDA could sustain up to~300% stretch- [41], double network gel (DN gel) [42], poly(N-acryloyl glycinamide) gel (PNAGA gel) [43], polyurethane (PEU gel) [44], polypyrrole-grafted chitosan gel (DCh-Ppy gel) [45], nanocomposite hydrogels (NC gel) [46], hydrophobic association hydrogels (HA gel) [47], bacterial cellulose gel (BC gel) [48] and skin [49][50][51].…”

Section: Resultsmentioning

confidence: 99%