Double Mizoroki–Heck Arylation of Terminal Alkenes in the Presence of “Ligand-Free” Palladium Catalytic Systems

Abstract

One-pot sequential double arylation of terminal alkenes with aryl halides to give trisubstituted derivatives is reported. The proposed approach is more advantageous than the known methods due to the use of a combination of low reactive but available aryl bromides or aryl chlorides and palladium-based “ligand-free” catalytic system.