Double‐Layered Plasmonic–Magnetic Vesicles by Self‐Assembly of Janus Amphiphilic Gold–Iron(II,III) Oxide Nanoparticles

Abstract

Janus nanoparticles (JNPs) offer unique features, including the precisely controlled distribution of compositions, surface charges, dipole moments, modular and combined functionalities, which enable excellent applications that are unavailable to their symmetrical counterparts. Assemblies of NPs exhibit coupled optical, electronic and magnetic properties that are different from single NPs. Herein, we report a new class of double-layered plasmonic-magnetic vesicle assembled from Janus amphiphilic Au-Fe O NPs grafted with polymer brushes of different hydrophilicity on Au and Fe O surfaces separately. Like liposomes, the vesicle shell is composed of two layers of Au-Fe O NPs in opposite direction, and the orientation of Au or Fe O in the shell can be well controlled by exploiting the amphiphilic property of the two types of polymers.

Photoacoustic Imaging: Contrast Agents and Their Biomedical Applications

“…Nanoparticle assemblies possess magnetic, electronic, and optical properties that vary considerably from those of the corresponding single NPs. For example, Chen and co‐workers reported a double‐layer plasmonic–magnetic nanovesicle assembly that was prepared using different hydrophilic polymer brushes functionalized onto the Au and Fe 3 O 4 NP surfaces, respectively, forming Janus amphiphilic Au‐Fe 3 O 4 NPs . The location of the Fe 3 O 4 and Au NPs within the vesicular shell could be easily exchanged by adjusting the amphiphilicity of the conjugated polymer brushes (Figure M).…”

Biocompatible and pH‐Responsive Colloidal Surfactants with Tunable Shape for Controlled Interfacial Curvature

“…Various methods have been explored to prepare the particles, such as topological surface modification, self‐assembly, controlled phase separation, electrodynamic co‐jetting, microfluidic engineering, and controlled surface nucleation . However, the preparation of biocompatible amphiphilic Janus particles through a facile method has barely been addressed, which greatly limits their biorelated application .…”

Plasmonic Gold Nanovesicles for Biomedical Applications

“…Janus NPs are a special class of anisotropic NPs in which two halves have distinct physicochemical properties . Song et al prepared a double‐layered (DL) plasmonic–magnetic vesicle with Janus GN‐Fe 3 O 4 as the core . As shown in Figure a,b, the size of Janus GN‐Fe 3 O 4 is about 6.5–6.0 nm, and its LSPR peak showed an obvious red‐shift compared with pure GN.…”

“…TEM‐element mapping images of c) the DL‐Ve 1, d) DL‐Ve 2, and e) ML‐Ve 3. f) UV–vis spectra of DL‐Ve 1 and 2, and ML‐Ve 3 and Janus GN‐Fe 3 O 4 . Adapted with permission . Copyright 2017, Wiley‐VCH.…”